2′-OMe-UMP triethylamine
Based on 1 Customer Validation
2′-OMe-UMP triethylamine is a primer extension terminator. When 2′-OMe-UMP triethylamine is present at the -1 position of the primer chain, its 2′-OMe group sterically clashes with the base of the next NTP at the active site (+1 position). This clash weakens the base-stacking interaction between the +1 position and the -1 position, thereby reducing the binding affinity of the next substrate.
For research use only. We do not sell to patients.
- Formula: C22H45N4O9P
- Molecular Weight:540.59
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
Chemical Information
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Appearance Solid
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Molecular Weight 540.59
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Formula C22H45N4O9P
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SMILES
CCN(CC)CC.CCN(CC)CC.O[C@H]1[C@@H](OC)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COP(O)(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
H2O : 100 mg/mL (184.98 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
Purity & Documentation
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.8498 mL | 9.2492 mL | 18.4983 mL | 46.2458 mL |
| 5 mM | 0.3700 mL | 1.8498 mL | 3.6997 mL | 9.2492 mL | |
| 10 mM | 0.1850 mL | 0.9249 mL | 1.8498 mL | 4.6246 mL | |
| 15 mM | 0.1233 mL | 0.6166 mL | 1.2332 mL | 3.0831 mL | |
| 20 mM | 0.0925 mL | 0.4625 mL | 0.9249 mL | 2.3123 mL | |
| 25 mM | 0.0740 mL | 0.3700 mL | 0.7399 mL | 1.8498 mL | |
| 30 mM | 0.0617 mL | 0.3083 mL | 0.6166 mL | 1.5415 mL | |
| 40 mM | 0.0462 mL | 0.2312 mL | 0.4625 mL | 1.1561 mL | |
| 50 mM | 0.0370 mL | 0.1850 mL | 0.3700 mL | 0.9249 mL | |
| 60 mM | 0.0308 mL | 0.1542 mL | 0.3083 mL | 0.7708 mL | |
| 80 mM | 0.0231 mL | 0.1156 mL | 0.2312 mL | 0.5781 mL | |
| 100 mM | 0.0185 mL | 0.0925 mL | 0.1850 mL | 0.4625 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
2′-OMe-UMP triethylamine Related Classifications
HY-171516A Related Classifications
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