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2′-OMe-UMP

2′-OMe-UMP is a primer extension terminator. When 2′-OMe-UMP is present at the -1 position of the primer chain, its 2′-OMe group sterically clashes with the base of the next NTP at the active site (+1 position). This clash weakens the base-stacking interaction between the +1 position and the -1 position, thereby reducing the binding affinity of the next substrate.

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  • CAS No.: 4214-23-7
  • Formula: C10H15N2O9P
  • Molecular Weight:338.21
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • 2′-OMe-UMP Chemical Structure
    2′-OMe-UMP Chemical Structure
CAS No.: 4214-23-7
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  • 2′-OMe-UMP Chemical Structure
    2′-OMe-UMP Chemical Structure
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  • 2′-OMe-UMP