1. Apoptosis
  2. Apoptosis
  3. 3-O-Methylgallic acid

3-O-Methylgallic acid (Synonyms: 3,4-Dihydroxy-5-methoxybenzoic acid)

Cat. No.: HY-N2009 Purity: 97.32%
Handling Instructions

3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) is an anthocyanin metabolite and has potent antioxidant capacity. 3-O-methylgallic acid inhibits Caco-2 cell proliferation with an IC50 value of 24.1 μM. 3-O-methylgallic acid also induces cell apoptosis and has anti-cancer effects.

For research use only. We do not sell to patients.

3-O-Methylgallic acid Chemical Structure

3-O-Methylgallic acid Chemical Structure

CAS No. : 3934-84-7

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500 mg USD 50 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) is an anthocyanin metabolite and has potent antioxidant capacity. 3-O-methylgallic acid inhibits Caco-2 cell proliferation with an IC50 value of 24.1 μM. 3-O-methylgallic acid also induces cell apoptosis and has anti-cancer effects[1][2].

Molecular Weight

184.15

Formula

C₈H₈O₅

CAS No.

3934-84-7

SMILES

O=C(O)C1=CC(OC)=C(O)C(O)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (271.52 mM; Need ultrasonic)

H2O : 2.2 mg/mL (11.95 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.4304 mL 27.1518 mL 54.3036 mL
5 mM 1.0861 mL 5.4304 mL 10.8607 mL
10 mM 0.5430 mL 2.7152 mL 5.4304 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (13.58 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (13.58 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

3-O-Methylgallic acid3,4-Dihydroxy-5-methoxybenzoic acidApoptosisAnthocyaninmetaboliteantioxidantanti-proliferationapoptosisanti-cancerInhibitorinhibitorinhibit

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Product Name:
3-O-Methylgallic acid
Cat. No.:
HY-N2009
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