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Cat. No.: HY-W716241

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3',4'-Dihydroxytrimethoprim

3',4'-Dihydroxytrimethoprim is a Trimethoprim (HY-B0510) derivative. 3',4'-Dihydroxytrimethoprim forms via sequential O-demethylation of Trimethoprim in human liver microsomes. 3',4'-Dihydroxytrimethoprim can be used for metabolic research.

For research use only. We do not sell to patients.

CAS No.: 71525-06-9
Formula: C₁₂H₁₄N₄O₃
Molecular Weight:262.26

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

3',4'-Dihydroxytrimethoprim Chemical Structure

CAS No.: 71525-06-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
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Biological Activity

Description

In Vitro

3',4'-Dihydroxytrimethoprim can be used to study the metabolic pathway of Trimethoprim [1].
3',4'-Dihydroxytrimethoprim can be used as a substrate to study the activity of enzymes that metabolize specific drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS No. 71525-06-9
Molecular Weight 262.26
Formula C₁₂H₁₄N₄O₃
SMILES

OC1=C(C=C(C=C1O)CC2=CN=C(N=C2N)N)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. van Haandel L, et al. Urinary biomarkers of trimethoprim bioactivation in vivo following therapeutic dosing in children. Chem Res Toxicol. 2014;27(2):211-218. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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