3-Hydroxy carvedilol
3-Hydroxy carvedilol is an active compound.
For research use only. We do not sell to patients.
- CAS No.: 146574-43-8
- Formula: C24H26N2O5
- Molecular Weight:422.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
9.4 μM
Compound: 2; BM-910228; SB 211475
|
Inhibition of RyR2 R4496C mutant-mediated store overload-induced calcium release in HEK293 cells assessed as reduction in amplitude of spontaneous calcium oscillations by fura-2 AM dye based fluorescence assay
Inhibition of RyR2 R4496C mutant-mediated store overload-induced calcium release in HEK293 cells assessed as reduction in amplitude of spontaneous calcium oscillations by fura-2 AM dye based fluorescence assay
|
[PMID: 26584883] |
Chemical Information
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CAS No. 146574-43-8
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Molecular Weight 422.47
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Formula C24H26N2O5
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SMILES
OC1=C(OCC(CNCCOC2=C(OC)C=CC=C2)O)C3=C(NC4=C3C=CC=C4)C=C1
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Synonyms
SB 211475; BM 910228
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)