1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. 3'-NH2-ddT

3'-NH2-ddT  (Synonyms: 3′-Amino-2′,3′-dideoxythymidine)

Cat. No.: HY-W012077
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3'-NH2-ddT (3′-Amino-2′,3′-dideoxythymidine) is a monomeric raw material that can be used for nucleic acid synthesis.

For research use only. We do not sell to patients.

3'-NH2-ddT

3'-NH2-ddT Chemical Structure

CAS No. : 52450-18-7

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Description

3'-NH2-ddT (3′-Amino-2′,3′-dideoxythymidine) is a monomeric raw material that can be used for nucleic acid synthesis.

Cellular Effect
Cell Line Type Value Description References
D-38 ED50
100 μM
Compound: 1
In vitro cytotoxicity against human D-38 cells.
In vitro cytotoxicity against human D-38 cells.
[PMID: 6854592]
Huh-7 CC50
>100 μg/mL
Compound: 8
Cytotoxicity against human HuH7 cells by XTT assay
Cytotoxicity against human HuH7 cells by XTT assay
[PMID: 22178557]
L1210 ED50
0.8 μM
Compound: 3'-AdThd
Compound was tested in vitro for cytotoxicity against L1210 leukemia cells in tumor bearing mice.
Compound was tested in vitro for cytotoxicity against L1210 leukemia cells in tumor bearing mice.
[PMID: 2939245]
L929 ED50
3 μM
Compound: 1
in vitro cytotoxicity against mouse L cells.
in vitro cytotoxicity against mouse L cells.
[PMID: 6854592]
Molecular Weight

241.24

Formula

C10H15N3O4

CAS No.
SMILES

O=C(NC(C(C)=C1)=O)N1[C@@H]2O[C@H](CO)[C@@H](N)C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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The molarity calculator equation

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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3'-NH2-ddT
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HY-W012077
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