(4-Ethynylphenyl)methanol
Based on 1 Customer Validation
(4-Ethynylphenyl)methanol is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.67%
- CAS No.: 10602-04-7
- Formula: C9H8O
- Molecular Weight:132.16
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E22 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 10602-04-7
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Appearance <40°C Solid,>44°C Liquid
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Molecular Weight 132.16
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Formula C9H8O
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Color White to light yellow
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SMILES
C#CC1=CC=C(C=C1)CO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (756.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (241 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.5666 mL | 37.8329 mL | 75.6659 mL | 189.1646 mL |
| 5 mM | 1.5133 mL | 7.5666 mL | 15.1332 mL | 37.8329 mL | |
| 10 mM | 0.7567 mL | 3.7833 mL | 7.5666 mL | 18.9165 mL | |
| 15 mM | 0.5044 mL | 2.5222 mL | 5.0444 mL | 12.6110 mL | |
| 20 mM | 0.3783 mL | 1.8916 mL | 3.7833 mL | 9.4582 mL | |
| 25 mM | 0.3027 mL | 1.5133 mL | 3.0266 mL | 7.5666 mL | |
| 30 mM | 0.2522 mL | 1.2611 mL | 2.5222 mL | 6.3055 mL | |
| 40 mM | 0.1892 mL | 0.9458 mL | 1.8916 mL | 4.7291 mL | |
| 50 mM | 0.1513 mL | 0.7567 mL | 1.5133 mL | 3.7833 mL | |
| 60 mM | 0.1261 mL | 0.6305 mL | 1.2611 mL | 3.1527 mL | |
| 80 mM | 0.0946 mL | 0.4729 mL | 0.9458 mL | 2.3646 mL | |
| 100 mM | 0.0757 mL | 0.3783 mL | 0.7567 mL | 1.8916 mL |