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Cat. No.: HY-152434

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5-Hydroxymethyl-arauridine

5-Hydroxymethyl-arauridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis.

For research use only. We do not sell to patients.

CAS No.: 28608-82-4
Formula: C₁₀H₁₄N₂O₇
Molecular Weight:274.23

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

5-Hydroxymethyl-arauridine Chemical Structure

CAS No.: 28608-82-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

5-Hydroxymethyl-arauridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
Huh-7	CC₅₀	>100 μg/mL Compound: 18	Toxicity against human HuH7 cells after 2 days by [3H]thymidine incorporation assay Toxicity against human HuH7 cells after 2 days by [3H]thymidine incorporation assay	[PMID: 22664188]
Huh-7	CC₅₀	>100 μg/mL Compound: 18	Toxicity against human HuH7 cells after 2 days by XTT assay Toxicity against human HuH7 cells after 2 days by XTT assay	[PMID: 22664188]

Chemical Information

CAS No. 28608-82-4
Molecular Weight 274.23
Formula C₁₀H₁₄N₂O₇
SMILES

O=C(C(CO)=CN1[C@H]2[C@@H](O)[C@H](O)[C@@H](CO)O2)NC1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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