5-Methyluridine-2′-13C
5-Methyluridine-2′-13C is the 13C labeled 5-Methyluridine. 5-Methyluridine is a is an endogenous methylated nucleoside found in human flu.
For research use only. We do not sell to patients.
- CAS No.: 478510-98-4
- Formula: C913CH14N2O6
- Molecular Weight:259.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 478510-98-4
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Unlabeled Cas 1463-10-1
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Molecular Weight 259.22
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Formula C913CH14N2O6
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SMILES
O[C@H]1[13C@@H](O)[C@H](N2C(NC(C(C)=C2)=O)=O)O[C@@H]1CO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Yang TH, et al. Intracellular levels of S-adenosylhomocysteine but not homocysteine are highly correlated to the expression of nm23-H1 and the level of 5-methyldeoxycytidine in human hepatoma cells with different invasion activities. Nutr Cancer. 2006;55( [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)