6-Amino-1-hexanethiol hydrochloride

Cat. No.: HY-33462 Purity: ≥98.0%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

6-Amino-1-hexanethiol hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

6-Amino-1-hexanethiol hydrochloride Chemical Structure

CAS No. : 31098-40-5

Size	Stock	Quantity
Free Sample (0.1 - 0.2 mg)	Apply Now
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
250 mg	In-stock	Estimated Time of Arrival: December 31
500 mg	In-stock	Estimated Time of Arrival: December 31
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	In-stock	Estimated Time of Arrival: December 31
10 g	Get quote
50 g	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

View All PROTAC Linkers Isoform Specific Products:

View All Isoforms

PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

Biological Activity
Purity & Documentation
Customer Review

Description

6-Amino-1-hexanethiol hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E428 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

169.72

Formula

C₆H₁₆ClNS

CAS No.

31098-40-5

Appearance

Solid

Color

Off-white to light yellow

SMILES

SCCCCCCN.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 17.5 mg/mL (103.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.8921 mL	29.4603 mL	58.9206 mL
5 mM	1.1784 mL	5.8921 mL	11.7841 mL
10 mM	0.5892 mL	2.9460 mL	5.8921 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (238 KB) SDS (394 KB)

COA (241 KB) HNMR (126 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.8921 mL	29.4603 mL	58.9206 mL	147.3014 mL
	5 mM	1.1784 mL	5.8921 mL	11.7841 mL	29.4603 mL
	10 mM	0.5892 mL	2.9460 mL	5.8921 mL	14.7301 mL
	15 mM	0.3928 mL	1.9640 mL	3.9280 mL	9.8201 mL
	20 mM	0.2946 mL	1.4730 mL	2.9460 mL	7.3651 mL
	25 mM	0.2357 mL	1.1784 mL	2.3568 mL	5.8921 mL
	30 mM	0.1964 mL	0.9820 mL	1.9640 mL	4.9100 mL
	40 mM	0.1473 mL	0.7365 mL	1.4730 mL	3.6825 mL
	50 mM	0.1178 mL	0.5892 mL	1.1784 mL	2.9460 mL
	60 mM	0.0982 mL	0.4910 mL	0.9820 mL	2.4550 mL
	80 mM	0.0737 mL	0.3683 mL	0.7365 mL	1.8413 mL
	100 mM	0.0589 mL	0.2946 mL	0.5892 mL	1.4730 mL