6-Amino-1-hexanethiol hydrochloride
Based on 1 Customer Validation
6-Amino-1-hexanethiol hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: ≥98.0%
- CAS No.: 31098-40-5
- Formula: C6H16ClNS
- Molecular Weight:169.72
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All PROTAC Linkers Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E428 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 31098-40-5
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Appearance Solid
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Molecular Weight 169.72
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Formula C6H16ClNS
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Color Off-white to light yellow
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SMILES
SCCCCCCN.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 17.5 mg/mL (103.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (238 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.8921 mL | 29.4603 mL | 58.9206 mL | 147.3014 mL |
| 5 mM | 1.1784 mL | 5.8921 mL | 11.7841 mL | 29.4603 mL | |
| 10 mM | 0.5892 mL | 2.9460 mL | 5.8921 mL | 14.7301 mL | |
| 15 mM | 0.3928 mL | 1.9640 mL | 3.9280 mL | 9.8201 mL | |
| 20 mM | 0.2946 mL | 1.4730 mL | 2.9460 mL | 7.3651 mL | |
| 25 mM | 0.2357 mL | 1.1784 mL | 2.3568 mL | 5.8921 mL | |
| 30 mM | 0.1964 mL | 0.9820 mL | 1.9640 mL | 4.9100 mL | |
| 40 mM | 0.1473 mL | 0.7365 mL | 1.4730 mL | 3.6825 mL | |
| 50 mM | 0.1178 mL | 0.5892 mL | 1.1784 mL | 2.9460 mL | |
| 60 mM | 0.0982 mL | 0.4910 mL | 0.9820 mL | 2.4550 mL | |
| 80 mM | 0.0737 mL | 0.3683 mL | 0.7365 mL | 1.8413 mL | |
| 100 mM | 0.0589 mL | 0.2946 mL | 0.5892 mL | 1.4730 mL |