7-Hydroxywarfarin-d₅

Name: 7-Hydroxywarfarin-d 5
Brand: MedChemExpress
SKU: HY-134938S
Rating: 4.5 (1 reviews)

Cat. No.: HY-134938S Purity: 98.05%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

7-Hydroxywarfarin-d₅ is the deuterium labeled 7-Hydroxywarfarin[1].

For research use only. We do not sell to patients.

7-Hydroxywarfarin-d<sub>5</sub> Chemical Structure

7-Hydroxywarfarin-d₅ Chemical Structure

CAS No. : 94820-65-2

Size	Price	Stock	Quantity
1 mg	USD 190	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 570	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 980	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

7-Hydroxywarfarin-d₅ is the deuterium labeled 7-Hydroxywarfarin[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

329.36

Formula

C₁₉H₁₁D₅O₅

CAS No.

94820-65-2

Appearance

Solid

Color

White to off-white

SMILES

CC(CC(C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])C2=C(C3=CC=C(O)C=C3OC2=O)O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (303.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.0362 mL	15.1810 mL	30.3619 mL
5 mM	0.6072 mL	3.0362 mL	6.0724 mL
10 mM	0.3036 mL	1.5181 mL	3.0362 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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Dosing volume
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μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.05%

Select Batch:

Data Sheet (274 KB) SDS (416 KB)

COA (255 KB) HNMR (128 KB) RP-HPLC (154 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.0362 mL	15.1810 mL	30.3619 mL	75.9048 mL
	5 mM	0.6072 mL	3.0362 mL	6.0724 mL	15.1810 mL
	10 mM	0.3036 mL	1.5181 mL	3.0362 mL	7.5905 mL
	15 mM	0.2024 mL	1.0121 mL	2.0241 mL	5.0603 mL
	20 mM	0.1518 mL	0.7590 mL	1.5181 mL	3.7952 mL
	25 mM	0.1214 mL	0.6072 mL	1.2145 mL	3.0362 mL
	30 mM	0.1012 mL	0.5060 mL	1.0121 mL	2.5302 mL
	40 mM	0.0759 mL	0.3795 mL	0.7590 mL	1.8976 mL
	50 mM	0.0607 mL	0.3036 mL	0.6072 mL	1.5181 mL
	60 mM	0.0506 mL	0.2530 mL	0.5060 mL	1.2651 mL
	80 mM	0.0380 mL	0.1898 mL	0.3795 mL	0.9488 mL
	100 mM	0.0304 mL	0.1518 mL	0.3036 mL	0.7590 mL