8-Hydroxybergapten

Cat. No.: HY-N6010 Purity: 99.87%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

8-hydroxybergapten is O-methylated by cell-free extracts of Ruta cells to isopimpinellin, in reactions mediated by discrete O-methyltransferases. 8-hydroxybergapten has excellent anti-wrinkle effect.

For research use only. We do not sell to patients.

8-Hydroxybergapten Chemical Structure

CAS No. : 1603-47-0

Size	Price	Stock	Quantity
1 mg	USD 120	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 300	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Description

8-hydroxybergapten is O-methylated by cell-free extracts of Ruta cells to isopimpinellin, in reactions mediated by discrete O-methyltransferases. 8-hydroxybergapten has excellent anti-wrinkle effect^[1]^[2].

Molecular Weight

232.19

Formula

C₁₂H₈O₅

CAS No.

1603-47-0

Appearance

Solid

Color

Light yellow to green yellow

SMILES

COC1=C(C=CO2)C2=C(O)C(O3)=C1C=CC3=O

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (430.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.3068 mL	21.5341 mL	43.0682 mL
5 mM	0.8614 mL	4.3068 mL	8.6136 mL
10 mM	0.4307 mL	2.1534 mL	4.3068 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.87%

Select Batch:

Data Sheet (271 KB) SDS (251 KB)

COA (263 KB) HNMR (261 KB) LCMS (266 KB)

Handling Instructions (2659 KB)

References

[1]. Brown SA, et al. The biosynthesis of isopimpinellin. Can J Biochem. 1977 Jul;55(7):686-92. [Content Brief]

[2]. Mu-Hyun Jin, et al. Composition for promoting synthesis of collagen, and composition for external preparation for skin comprising the same.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.3068 mL	21.5341 mL	43.0682 mL	107.6704 mL
	5 mM	0.8614 mL	4.3068 mL	8.6136 mL	21.5341 mL
	10 mM	0.4307 mL	2.1534 mL	4.3068 mL	10.7670 mL
	15 mM	0.2871 mL	1.4356 mL	2.8712 mL	7.1780 mL
	20 mM	0.2153 mL	1.0767 mL	2.1534 mL	5.3835 mL
	25 mM	0.1723 mL	0.8614 mL	1.7227 mL	4.3068 mL
	30 mM	0.1436 mL	0.7178 mL	1.4356 mL	3.5890 mL
	40 mM	0.1077 mL	0.5384 mL	1.0767 mL	2.6918 mL
	50 mM	0.0861 mL	0.4307 mL	0.8614 mL	2.1534 mL
	60 mM	0.0718 mL	0.3589 mL	0.7178 mL	1.7945 mL
	80 mM	0.0538 mL	0.2692 mL	0.5384 mL	1.3459 mL
	100 mM	0.0431 mL	0.2153 mL	0.4307 mL	1.0767 mL

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

8-Hydroxybergapten1603-47-0OthersInhibitorinhibitorinhibit

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8-Hydroxybergapten

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