1. GPCR/G Protein
    Neuronal Signaling
  2. Opioid Receptor

BAN ORL 24 

Cat. No.: HY-13222 Purity: 95.07%
Handling Instructions

BAN ORL 24 is a potent and selective NOP receptor antagonist. (IC50 values are 0.27, 2500, 6700 and > 10000 nM for NOP, κ-, μ- and δ-receptors respectively).

For research use only. We do not sell to patients.
BAN ORL 24 Chemical Structure

BAN ORL 24 Chemical Structure

CAS No. : 1401463-54-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 158 In-stock
10 mg USD 144 In-stock
50 mg USD 540 In-stock
100 mg USD 960 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

BAN ORL 24 is a potent and selective NOP receptor antagonist. (IC50 values are 0.27, 2500, 6700 and > 10000 nM for NOP, κ-, μ- and δ-receptors respectively). IC50 value: 0.27 nM Target: NOP receptor BAN ORL 24 inhibits nociceptin-induced stimulation of [35S]-GTPγS binding and Ca2+ mobilization in CHO cells in vitro. BAN ORL 24 antagonizes NOP agonist-induced reduction in locomotor activity in vivo. Brain penetrant.

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 1.9743 mL 9.8715 mL 19.7429 mL
5 mM 0.3949 mL 1.9743 mL 3.9486 mL
10 mM 0.1974 mL 0.9871 mL 1.9743 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

506.51

Formula

C₂₇H₃₇Cl₂N₃O₂

CAS No.

1401463-54-4

SMILES

O=C([[email protected]@H]1N(CC2=CC=CC=C2)CCC1)NCCCN3CCC4(CC3)OCC5=C4C=CC=C5.[H]Cl.[H]Cl

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
BAN ORL 24
Cat. No.:
HY-13222
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