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ChX710 

Cat. No.: HY-112951
Handling Instructions

ChX710 could prime the type I interferon response to cytosolic DNA, which induces the ISRE promoter sequence, specific cellular Interferon-Stimulated Genes (ISGs), and the phosphorylation of Interferon Regulatory Factor (IRF) 3.

For research use only. We do not sell to patients.

ChX710 Chemical Structure

ChX710 Chemical Structure

Size Price Stock
5 mg USD 350 Get quote
10 mg USD 550 Get quote
25 mg USD 1100 Get quote
50 mg USD 1750 Get quote
100 mg USD 2750 Get quote

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

ChX710 could prime the type I interferon response to cytosolic DNA, which induces the ISRE promoter sequence, specific cellular Interferon-Stimulated Genes (ISGs), and the phosphorylation of Interferon Regulatory Factor (IRF) 3.

In Vitro

ChX710 treatment is found to efficiently prime the cellular response to DNA transfection via STING as assessed by strong synergistic effects on IFN-β expression at both transcriptional and protein levels [1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0922 mL 15.4612 mL 30.9224 mL
5 mM 0.6184 mL 3.0922 mL 6.1845 mL
10 mM 0.3092 mL 1.5461 mL 3.0922 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

323.39

Formula

C₁₈H₂₁N₅O

SMILES

O=C(NC(C)CN(C)C)C1=C(N=C(C2=CC=NC=C2)N3)C3=CC=C1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

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C1   V1   C2   V2

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Product Name:
ChX710
Cat. No.:
HY-112951
Quantity:

ChX710

Cat. No.: HY-112951