Complanatoside A
Complanatoside A is a flavonol glycoside isolated from Astragalus complanatus, and currently it is used as a quality control index for A. complanatus in the 2010 edition of the Chinese Pharmacopoeia.
For research use only. We do not sell to patients.
- CAS No.: 146501-37-3
- Formula: C27H30O18
- Molecular Weight:642.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
A simple and sensitive LC-MS/MS method is developed for the determination of complanatoside A in rat plasma over the range of 2.3–575 ng/mL. Complanatoside A is extracted from plasma by a protein precipitation procedure, separated by LC and detected by MS/MS in positive electrospray ionization mode. The lower limit of quantification is established at 2.3 ng/mL. Intra- and inter-day precisions (LLOQ, low-QC, med-QC and high-QC) are less than 7.9%, and accuracies are between 94.0 and 105.1%. Matrix effect is acceptable (97.9–103.0%) and extraction recovery is reproducible (88.5–94.4%). Complanatoside A is stable in the investigated conditions. The method is applied to the pharmacokinetics of complanatoside A in rats[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 146501-37-3
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Molecular Weight 642.52
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Formula C27H30O18
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SMILES
O=C1C(O[C@@H]([C@@H]([C@@H](O)[C@@H]2O)O)O[C@@H]2CO)=C(C3=CC(O)=C(O[C@@H]([C@@H]([C@@H](O)[C@@H]4O)O)O[C@@H]4CO)C(O)=C3)OC5=CC(O)=CC(O)=C15
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro:
DMSO : ≥ 35.7 mg/mL (55.56 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5564 mL | 7.7819 mL | 15.5637 mL | 38.9093 mL |
| 5 mM | 0.3113 mL | 1.5564 mL | 3.1127 mL | 7.7819 mL | |
| 10 mM | 0.1556 mL | 0.7782 mL | 1.5564 mL | 3.8909 mL | |
| 15 mM | 0.1038 mL | 0.5188 mL | 1.0376 mL | 2.5940 mL | |
| 20 mM | 0.0778 mL | 0.3891 mL | 0.7782 mL | 1.9455 mL | |
| 25 mM | 0.0623 mL | 0.3113 mL | 0.6225 mL | 1.5564 mL | |
| 30 mM | 0.0519 mL | 0.2594 mL | 0.5188 mL | 1.2970 mL | |
| 40 mM | 0.0389 mL | 0.1945 mL | 0.3891 mL | 0.9727 mL | |
| 50 mM | 0.0311 mL | 0.1556 mL | 0.3113 mL | 0.7782 mL |
Complanatoside A Related Classifications
HY-N0624 Related Classifications
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