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Eledoisin (Synonyms: Eledone peptide)

Cat. No.: HY-P0006 Purity: 99.37%
Handling Instructions

Eledoisin (Eledone peptide) is a specific agonist of NK2 and NK3 receptors.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Eledoisin Chemical Structure

Eledoisin Chemical Structure

CAS No. : 69-25-0

Size Price Stock Quantity
1 mg USD 60 In-stock
Estimated Time of Arrival: December 31
5 mg USD 250 In-stock
Estimated Time of Arrival: December 31
10 mg USD 420 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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Eledoisin (Eledone peptide) is a specific agonist of NK2 and NK3 receptors.

IC50 & Target

NK2 and NK3 receptors[1].

In Vitro

Eledoisin (Eledone peptide) increases the value recorded under basal conditions by 24.5±3.7%; this stimulation is significantly (P<0.01) lowered to 13.1±1.9% by the simultaneous presence of CP99994. The same protocol is also used to characterize the sensitivity of Eledoisin stimulation to 0.1 μM SR48968 or 0.1 μM SB222200. SR48968 significantly (P < 0.01) lower the stimulation by Eledoisin, while SB222200 has no effect. Eledoisin stimulation is reduced by CP99994 and SR48968, NK1 and NK2 antagonists, respectively[1].

In Vivo

Eledoisin (Eledone peptide; 0.1-1 nmol/kg) injected into rats produces a biphasic cardiovascular response that consists of an initial fall of systemic blood pressure (8-15 mm Hg) followed by a rise (20-22 mm Hg). Intracerebroventricular injection of Eledoisin produces an enhancement of grooming and scratching behavior in mice[2].

Molecular Weight








Sequence Shortening



Room temperature in continental US; may vary elsewhere.

Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 18.15 mg/mL (15.27 mM; Need ultrasonic and warming)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8415 mL 4.2073 mL 8.4147 mL
5 mM 0.1683 mL 0.8415 mL 1.6829 mL
10 mM 0.0841 mL 0.4207 mL 0.8415 mL
*Please refer to the solubility information to select the appropriate solvent.
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EledoisinEledone peptideOthersInhibitorinhibitorinhibit

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