1. GPCR/G Protein Neuronal Signaling
  2. Neurokinin Receptor
  3. Eledoisin

Eledoisin  (Synonyms: Eledone peptide)

Cat. No.: HY-P0006 Purity: 98.73%
COA Handling Instructions

Eledoisin (Eledone peptide) is a specific agonist of NK2 and NK3 receptors.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Eledoisin Chemical Structure

Eledoisin Chemical Structure

CAS No. : 69-25-0

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1 mg USD 60 In-stock
5 mg USD 250 In-stock
10 mg USD 420 In-stock
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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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Eledoisin (Eledone peptide) is a specific agonist of NK2 and NK3 receptors.

IC50 & Target





In Vitro

Eledoisin (Eledone peptide) increases the value recorded under basal conditions by 24.5±3.7%; this stimulation is significantly (P<0.01) lowered to 13.1±1.9% by the simultaneous presence of CP99994. The same protocol is also used to characterize the sensitivity of Eledoisin stimulation to 0.1 μM SR48968 or 0.1 μM SB222200. SR48968 significantly (P < 0.01) lower the stimulation by Eledoisin, while SB222200 has no effect. Eledoisin stimulation is reduced by CP99994 and SR48968, NK1 and NK2 antagonists, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Eledoisin (Eledone peptide; 0.1-1 nmol/kg) injected into rats produces a biphasic cardiovascular response that consists of an initial fall of systemic blood pressure (8-15 mm Hg) followed by a rise (20-22 mm Hg). Intracerebroventricular injection of Eledoisin produces an enhancement of grooming and scratching behavior in mice[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight








Sequence Shortening



Room temperature in continental US; may vary elsewhere.


Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 18.15 mg/mL (15.27 mM; Need ultrasonic and warming)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8415 mL 4.2073 mL 8.4147 mL
5 mM 0.1683 mL 0.8415 mL 1.6829 mL
10 mM 0.0841 mL 0.4207 mL 0.8415 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
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Eledoisin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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