1. GPCR/G Protein
  2. Ras
  3. KRAS G12C inhibitor 5

KRAS G12C inhibitor 5 

Cat. No.: HY-114168
Handling Instructions

KRAS G12C inhibitor 5 is a KRas G12C inhibitor extracted from patent WO2017201161A1, Compound example 147.

For research use only. We do not sell to patients.

KRAS G12C inhibitor 5 Chemical Structure

KRAS G12C inhibitor 5 Chemical Structure

CAS No. : 2158297-63-1

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KRAS G12C inhibitor 5 is a KRas G12C inhibitor extracted from patent WO2017201161A1, Compound example 147[1].

IC50 & Target[1]

KRas G12C


In Vitro

Kirsten Rat Sarcoma 2 Viral Oncogene Homolog (KRas) is a small GTPase and a member of the Ras family of oncogenes. KRas serves a molecular switch cycling between inactive (GDP -bound) and active (GTP -bound) states to transduce upstream cellular signals received from multiple tyrosine kinases to downstream effectors to regulate a wide variety of processes, including cellular proliferation[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight







N#CC[[email protected]@H]1N(C(C=C)=O)CCN(C2=C3C(CN(C4=C5C=CC=CC5=CC=C4)CC3)=NC(OC[[email protected]]6N(C)CCC6)=N2)C1


Room temperature in continental US; may vary elsewhere.


Please store the product under the recommended conditions in the Certificate of Analysis.

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KRAS G12C inhibitor 5RasInhibitorinhibitorinhibit

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