Magnoliaceae

Magnoloside A (compound 4) is a main phenylethanoid glycoside in Houpo. Magnoloside A can be used in the research of functional dyspepsia (FD).

Kobusin is a bisepoxylignan isolated from the Pnonobio biondii Pamp. Kobusin is an activator of CFTR and CaCCgie chloride channels and a inhibitor of ANO1/CaCC (calcium-activated chloride channel) channel.

Veraguensin is a lignan compound derived from Magnolia sp.. Veraguensin can inhibit bone resorption

Deoxygeraniol, a monoterpenoid, has been reported in Camellia sinensis, Magnolia sieboldii, and Zingiber officinale. It is commonly used as an intermediate in the synthesis of fragrances or flavorings.

Magnolia denudata polysaccharide is a polysaccharide derived from Magnolia denudata.

Magnolia biondii polysaccharide is a polysaccharide derived from Magnolia biondii.

Michelia figo polysaccharide is a polysaccharide derived from Michelia figo.

Bornesitol is a natural cytotoxic agent found in Michelia compressa var. lanyuensis. Bornesitol exhibits cytotoxic and antiproliferative activities, and can be used in melanoma research.

Tetradecanenitrile is a nitrogen-containing saturated long-chain aliphatic nitrile that can be found in Pseudomonas veronii R02. Tetradecanenitrile can be used for the research of multiresistant Staphylococcus aureus infection.

Sesaminone is a lignan found in the leaves of Magnolia coco.

Cyathisterol is a steroidal compound that inhibits LPS (HY-D1056)-induced nitric oxide production. Cyathisterol can be used for the research of inflammatory diseases.

(+)-Fargesin is a natural lignan.

Michelenolide is an antioxidant and ferrous ion chelator. Michelenolide can be found in the stems of Michelia alba, with moderate antioxidant activity, moderate ferrous ion chelating properties.

11βh,13-Dihydroparthenolide (Compound 314) is a metabolite of Parthenolide (HY-N0141), which can be produced by biotransformation of filamentous fungi.

Calceolarioside C is a phenylpropanoid glycoside that can be found in the aerial parts of Calceolaria hypericina.

N-Acetylnornuciferine is an aporphine alkaloid, whose family members possess potential antibacterial, antiviral, antioxidant, or anticancer activities. N-Acetylnornuciferine can be extracted from the dried roots of Liriodendron tulipifera (American tulip tree, a plant of the Magnoliaceae family) using ethanol.

Sanleng acid is an unsaturated fatty acid compound that can be isolated from the hexane extract of Magnolia sieboldii (MsHE). MsHE can inhibit the expression of inflammatory mediators (such as COX-2) and pro-inflammatory cytokines (such as TNF-α, IL-1β), and increase the expression of tight junction proteins (claudin-4, claudin-5) to protect epithelial cell barrier function, thus exerting anti-inflammatory activity. Related compounds may be used in research related to reflux esophagitis (RE).

Phenylethyl isovalerate is a synthetic flavoring substance with very low acute oral toxicity. Phenylethyl isovalerate after long-term low-dose intake increases the activity of alanine aminotransferase (ALT) and the level of sulfhydryl groups in the serum, but decreases the activity of cholinesterase (ChE).

Magnotriol B is a cholinesterase inhibitor with IC₅₀ values of 12.63 nM and 14.5 nM against AChE and BChE, respectively. Magnotriol B also exhibits significant NO inhibitory activity with an IC₅₀ of 2.02 μM. Magnotriol B can be used in the research of neurodegenerative and inflammatory diseases.

Magnolignan I is a phenolic compound and a dilignan, which can be isolated from Magnoliae Cortex produced in China.