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  5. Michelia compressa (Maxim.) Sarg.
  6. Bornesitol

Bornesitol is a natural cytotoxic agent found in Michelia compressa var. lanyuensis. Bornesitol exhibits cytotoxic and antiproliferative activities, and can be used in melanoma research.

For research use only. We do not sell to patients.

Bornesitol

Bornesitol Chemical Structure

CAS No. : 484-71-9

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Bornesitol Related Antibodies

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Description

Bornesitol is a natural cytotoxic agent found in Michelia compressa var. lanyuensis. Bornesitol exhibits cytotoxic and antiproliferative activities, and can be used in melanoma research[1].

In Vitro

Bornesitol (1-100 μM; 24 h) shows no cytotoxicity against B16F10 melanoma cells at concentrations of 1 μM or 10 μM after 24 h of incubation, but induces cytotoxicity at a concentration of 100 μM[1].
Bornesitol (5 μM; 48 h) weakly inhibits tyrosinase activity in B16F10 melanoma cells after incubation at 5 μM for 48 h, with an inhibition rate of 3.06%[1].
Bornesitol (5 μM; 48 h) exerts only an extremely weak inhibitory effect on melanin content in B16F10 melanoma cells, with an inhibition rate of 0.89% after 48 h of incubation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Bornesitol Related Antibodies

Cell Viability Assay[1]

Cell Line: B16F10 melanoma cells
Concentration: 1 μM; 10 μM; 100 μM
Incubation Time: 24 h
Result: Did not reduce B16F10 cell viability relative to vehicle control at 1 μM and 10 μM.
Caused cytotoxicity, reducing cell viability relative to vehicle control at 100 μM.
Molecular Weight

194.18

Formula

C7H14O6
CAS No.
SMILES

O(C)[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Bornesitol Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bornesitol484-71-9OthersMichelia compressa var. lanyuensismelanintyrosinaseB16F10 melanoma cellsInhibitorinhibitorinhibit

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