Triterpenes

Neopanaxadiol, an aglycone of protopanaxadiol type ginsenosides, has the potential for Alzheimer's disease research.

β-D-glucopyranosyl-[α-L-rhamnopyranosyl-(1→3)-βD-glucuronopyranosyl-(1→3)]-3β-hydroxyolean-12-ene28-oate, as a saponin, has a glucuronic acid attached to carbon C-3 and is isolated from S. simplex.

Mogroside III A2 is a cucurbitane glycoside. Mogroside III A2 can inhibit Epstein-Barr virus early antigen (EBV-EA) activation. Mogroside III A2 shows weak inhibitory effects on activation of NOR 1.

Soyasapogenol D is a methyl-trimethylsilyl derivative of the sapogenin.

Achyranthoside C is a triterpenoid saponin found in the roots of Achyranthese bidentata Bl..

Araloside C is a natural saponin that is mainly isolated from Aralia elata. Araloside C exerts extensive anti-inflammatory properties. Araloside C exhibits protective effects against myocardial ischaemia/reperfusion injury.

(2α,3β)-Olean-12-ene-2,3-diol (Compound 3) is a triterpenoid with lupane, oleanane, and ursane skeleton.

3β,6α,12β-Dammar-E-20(22)-ene-3,6,12,25-tetraol, a SIRT1 activator, exhibits significant stimulation of SIRT1 activity. Anti-tumor activity.

Prosaikogenin H is an intestinal metabolite of saikosaponin with a weak hemolytic activity.

Raddeanoside R17 (Pulchinenoside E3) is a saponin compound that can be isolated from the root of Pulsatilla koreana. Raddeanoside R17 shows anti-inflammatory effects.

Pulchinenoside E2 is a triterpenoid saponin. Pulchinenoside E2 inhibits the phosphorylation of STAT3 and JAK2, blocks the nuclear translocation and transcriptional activity of STAT3, and suppresses STAT3-dependent mitochondrial oxidative phosphorylation. Pulchinenoside E2 inhibits invasion, migration and autophagy of triple-negative breast cancer cells. Pulchinenoside E2 can be used in research related to triple-negative breast cancer.

Pulsatilloside E (Chinensioside B) is a triterpenoidal saponin isolated from the roots of Pulsatilla chinensis (Ranunculaceae).

Isocucurbitacin B is a natural terpenoid compound found in Pedicellus Melo. Isocucurbitacin B can inhibit the PI3K/AKT, MAPK, and STAT3 signaling pathways and downregulate CAV1 expression. Isocucurbitacin B can inhbit cancer cell proliferation, migration and invision. Isocucurbitacin B can induce apoptosis and cause G2/M phase arrest. Isocucurbitacin B can decrease intracellular cholesterol and PH levels and increase intracellular calcium levels. Isocucurbitacin B can be used for the research of cancer, such as glioma^[1][2].

Lucidenic acid E is a terpenoid from Ganoderma lucidum.

5,6-Didehydroginsenoside Rd is a dammarane-type saponin isolated from the dried roots of Panax notoginseng.

11-Oxomogroside IV is a natural compound that could be found in the fruits of Siraitia grosvenori.