Verbenaceae Extract

4′-Hydroxywogonin (8-Methoxyapigenin), a flavonoid, could be isolated from a variety of plants including Scutellaria barbata and Verbena littoralis. 4′-Hydroxywogonin has anti-inflammatory activity via TAK1/IKK/NF-κB, MAPKs and PI3/AKT signaling pathways. 4′-Hydroxywogonin inhibits angiogenesis by disrupting PI3K/AKT signaling. 4′-Hydroxywogonin inhibits cell proliferation and induces apoptosis.

Penduletin is a flavone, that can be isolated from Brickelia pendula and Vitex negundo. Penduletin shows anticancer activity. Penduletin induces apoptosis in the cancer cells through ROS generation.

Cornoside is a phenolic glycoside and has inhibitory effect on rat lens aldose reductase (AR) with an IC₅₀ of 150 μM.

Coumaran (Standard) is the analytical standard of Coumaran. This product is intended for research and analytical applications. Coumaran (2,3-Dihydrobenzofuran) is an AChE inhibitor with antileishmanial activity. Coumaran may acquire antiparasitic capabilities through activation of macrophages and exert immunomodulatory activity. Coumaran can be used as a biopesticide..

Verbena officinalis polysaccharide is a polysaccharide derived from Verbena officinalis.

5,4'-Dihydroxy-6,7,3',5'-tetramethoxyflavone (Compound 3) is a flavonoid compound that can be isolated from the leaves of *Lantana montevidensis*. 5,4'-Dihydroxy-6,7,3',5'-tetramethoxyflavone possesses potential antioxidant, anti-inflammatory and anti-tumor activities, and can be used in the research of inflammation and cancer.

Acacetin 7-glucurono-(1→2)-glucuronide (compound 12) is a flavonoid compound present in the aerial parts of Callicarpa kwangtungensis Chun.

3′,8-Dimethoxy-4′,5,7-trihydroxyflavone (Compound 3) is a flavonoid compound that can be isolated from the aerial parts of Verbena littoralis.

Vitedoamine A is a Phenylnaphthalene-type lignan alkaloid. Vitedoamine A can be isolated from Vitex negundo. Vitedoamine A inhibits the activity of IKKβ with an IC₅₀ value of 39 μM. Vitedoamine A could inhibit the transcriptional activity of NF-κB, and suppress the production of NO and reduce the expressions of inflammatory cytokines (IL-1β, IL-6, and TNF-α). Vitedoamine A inhibits the phosphorylation of IKKα/β and p65, and prevents the degradation of IκBα. Vitedoamine A possesses anti-rheumatoid arthritis capacity.

(9S)-4-Oxo-7,8-dihydro-β-ionol (compound 6) is an apocarotenoid that can be found in the leaves of Tectona grandis.

Blumenol C is a natural sesquiterpene.

Breynioside A is a natural phenolic compound.

Negundonorin A is a natural triterpene.

3α,30-Diacetoxy-12α-hydroxy-23-oxoeupha-7,24-dien-21,16β-olid-28-oic acid 28-O-β-D-glucopyranosyl ester is a natural triterpene.

Teuvincenone H is a rosinane-type diterpenoid natural product that can be isolated from Daphne plants.

Icterogenin is a selective inhibitor targeting the Bcl-XL/Bak BH3 domain peptide interaction and exhibits anti-leukemic activity. Icterogenin regulates protein interactions and affects tumor cell survival. Icterogenin is an oleanane-type triterpenoid compound that can be isolated from Lantana camara and is useful in the field of anti-tumor drug development.

Thellungianate is a flavone-O-glycoside. Thellungianate can be isolated from Tectona grandis leaves.

Clerodendrin A is a diterpenoid bitter component that can be extracted from Clerodendron tricotomum. Clerodendrin A usually has anti feeding activity as a defense substance.

6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene (Compound 6) is a diterpenoid found in Premna obtusifolia with antibacterial activity. 6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene can significantly inhibit the release of the inflammatory mediator NO, with an IC₅₀ value of 29.1 μM. 6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene can be used for the researches of infection and inflammation.

Tiglic acid (Standard) is the analytical standard of Tiglic acid (HY-W012999). This product is intended for research and analytical applications. Tiglic acid is a monocarboxylic unsaturated organic acid. Tiglic acid can be isolated from croton oil. Tiglic acid agonizes FFA2 and upregulates PYY expression. Tiglic acid derivatives have anti-inflammatory activity. Tiglic acid can be used in the research of obesity, diabetes, and inflammatory diseases.