Icterogenin
Icterogenin is a selective inhibitor targeting the Bcl-XL/Bak BH3 domain peptide interaction and exhibits anti-leukemic activity. Icterogenin regulates protein interactions and affects tumor cell survival. Icterogenin is an oleanane-type triterpenoid compound that can be isolated from Lantana camara and is useful in the field of anti-tumor drug development.
For research use only. We do not sell to patients.
- CAS No.: 561-47-7
- Formula: C35H52O6
- Molecular Weight:568.78
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Bcl-xL |
Icterogenin exhibits cytotoxicity against HL-60 human promyelocytic leukemia cells, with IC50 values ranging from 1.16 to 68.4 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 561-47-7
-
Molecular Weight 568.78
-
Formula C35H52O6
-
SMILES
OC([C@@]([C@@H](C1)OC(/C(C)=C\C)=O)(CC[C@]23C)[C@](CC1(C)C)([H])C2=CC[C@@]4([H])[C@]3(CC[C@]([C@](C)5CO)([H])[C@@]4(CCC5=O)C)C)=O
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Icterogenin Related Classifications
HY-N9826 Related Classifications
Powered by Bioz