1. Protein Tyrosine Kinase/RTK
  2. ALK

PF-06260182 (Synonyms: 2-Keto Crizotinib; PF06260182; PF 06260182)

Cat. No.: HY-13320
Handling Instructions

PF-06260182 is an active lactam metabolite of crizotinib.

For research use only. We do not sell to patients.

PF-06260182 Chemical Structure

PF-06260182 Chemical Structure

CAS No. : 1415558-82-5

Size Stock
250 mg Get quote
500 mg Get quote

* Please select Quantity before adding items.

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

PF-06260182 is an active lactam metabolite of crizotinib.

In Vitro

PF-06260182 is active and considerably less potent than crizotinib, and it is not thought to contribute significantly to the in vivo activity of crizotinib.

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1537 mL 10.7684 mL 21.5369 mL
5 mM 0.4307 mL 2.1537 mL 4.3074 mL
10 mM 0.2154 mL 1.0768 mL 2.1537 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

464.32

Formula

C₂₁H₂₀Cl₂FN₅O₂

CAS No.

1415558-82-5

SMILES

O=C1CC(N2N=CC(C3=CC(O[[email protected]](C)C4=C(Cl)C(F)=CC=C4Cl)=C(N)N=C3)=C2)CCN1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
PF-06260182
Cat. No.:
HY-13320
Quantity:

PF-06260182

Cat. No.: HY-13320