1. Protein Tyrosine Kinase/RTK
  2. ALK

2-Keto Crizotinib (Synonyms: PF-06260182)

Cat. No.: HY-13320
Handling Instructions

2-Keto Crizotinib (PF-06260182) is an active lactam metabolite of crizotinib.

For research use only. We do not sell to patients.

2-Keto Crizotinib Chemical Structure

2-Keto Crizotinib Chemical Structure

CAS No. : 1415558-82-5

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

2-Keto Crizotinib (PF-06260182) is an active lactam metabolite of crizotinib.

In Vitro

2-Keto Crizotinib (PF-06260182) is active and considerably less potent than crizotinib, and it is not thought to contribute significantly to the in vivo activity of crizotinib.

References
Molecular Weight

464.32

Formula

C₂₁H₂₀Cl₂FN₅O₂

CAS No.

1415558-82-5

SMILES

O=C1CC(N2N=CC(C3=CC(O[[email protected]](C)C4=C(Cl)C(F)=CC=C4Cl)=C(N)N=C3)=C2)CCN1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
2-Keto Crizotinib
Cat. No.:
HY-13320
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2-Keto Crizotinib

Cat. No.: HY-13320