2-Keto Crizotinib
Based on 1 publication(s) in Google Scholar
2-Keto Crizotinib (PF-06260182) is an active lactam metabolite of crizotinib.
For research use only. We do not sell to patients.
- CAS No.: 1415558-82-5
- Formula: C21H20Cl2FN5O2
- Molecular Weight:464.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) 2-Keto Crizotinib
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Biological Activity
2-Keto Crizotinib (PF-06260182) is active and considerably less potent than crizotinib, and it is not thought to contribute significantly to the in vivo activity of crizotinib.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1415558-82-5
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Molecular Weight 464.32
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Formula C21H20Cl2FN5O2
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SMILES
O=C1CC(N2N=CC(C3=CC(O[C@H](C)C4=C(Cl)C(F)=CC=C4Cl)=C(N)N=C3)=C2)CCN1
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Synonyms
PF-06260182
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Gene
Selenoprotein S regulates tumorigenesis of clear cell renal cell carcinoma through AKT/ GSK3β/NF-κB signaling pathway. [Abstract]2022 Jul 20;832:146559. PMID: 35569765
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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