1. Protein Tyrosine Kinase/RTK
  2. ALK
  3. 2-Keto Crizotinib

2-Keto Crizotinib (Synonyms: PF-06260182)

Cat. No.: HY-13320
Handling Instructions

2-Keto Crizotinib (PF-06260182) is an active lactam metabolite of crizotinib.

For research use only. We do not sell to patients.

2-Keto Crizotinib Chemical Structure

2-Keto Crizotinib Chemical Structure

CAS No. : 1415558-82-5

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Description

2-Keto Crizotinib (PF-06260182) is an active lactam metabolite of crizotinib.

In Vitro

2-Keto Crizotinib (PF-06260182) is active and considerably less potent than crizotinib, and it is not thought to contribute significantly to the in vivo activity of crizotinib.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

464.32

Formula

C₂₁H₂₀Cl₂FN₅O₂

CAS No.

1415558-82-5

SMILES

O=C1CC(N2N=CC(C3=CC(O[[email protected]](C)C4=C(Cl)C(F)=CC=C4Cl)=C(N)N=C3)=C2)CCN1

Shipping

Room temperature in continental US; may vary elsewhere

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
2-Keto Crizotinib
Cat. No.:
HY-13320
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2-Keto Crizotinib

Cat. No.: HY-13320