Pamatolol

Cat. No.: HY-U00019: FAQs
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Pamatolol is a cardioselective beta-adrenoceptor antagonist without sympathomimetic activity.

For research use only. We do not sell to patients.

Pamatolol Chemical Structure

CAS No. : 59110-35-9

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α adrenergic receptor β adrenergic receptor

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Description	Pamatolol is a cardioselective beta-adrenoceptor antagonist without sympathomimetic activity.
In Vivo	Pamatolol is well absorbed in the gastro-intestinal tract and excreted in the urine of man, dogs, rats and mice after oral administration, mainly in unchanged form, within 24 hrs^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight	310.39
Formula	C₁₆H₂₆N₂O₄
CAS No.	59110-35-9
SMILES	O=C(OC)NCCC1=CC=C(OCC(O)CNC(C)C)C=C1
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (263 KB) Handling Instructions (2659 KB)
References	[1]. Hoffmann KJ, et al. Species differences in the metabolism of pamatolol, a cardioselective beta--adrenoceptor antagonist. Eur J Drug Metab Pharmacokinet. 1979;4(3):163-73. [Content Brief]

Animal Administration
^[1]

Three male Sprague-Dawley rats weighing 200-250 g are given pamatolol-sulphate dissolved in water at a dose of 50 mg/kg (10 μCi/mg) by means of a stomach tube. The rats are housed in metabolic cages that allows for separate collection of urine and feces for a 24 hr period. They are given a commercial pellet diet and drinking water ad libitum.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References

[1]. Hoffmann KJ, et al. Species differences in the metabolism of pamatolol, a cardioselective beta--adrenoceptor antagonist. Eur J Drug Metab Pharmacokinet. 1979;4(3):163-73. [Content Brief]

Pamatolol Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pamatolol59110-35-9Adrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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Pamatolol

Pamatolol Related Antibodies

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