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Cat. No.: HY-U00019

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Pamatolol

Pamatolol is a cardioselective beta-adrenoceptor antagonist without sympathomimetic activity.

For research use only. We do not sell to patients.

CAS No.: 59110-35-9
Formula: C₁₆H₂₆N₂O₄
Molecular Weight:310.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

Pamatolol Chemical Structure

CAS No.: 59110-35-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Protocol
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Pamatolol is a cardioselective beta-adrenoceptor antagonist without sympathomimetic activity.

All Adrenergic Receptor Isoforms :

In Vivo

Pamatolol is well absorbed in the gastro-intestinal tract and excreted in the urine of man, dogs, rats and mice after oral administration, mainly in unchanged form, within 24 hrs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 59110-35-9
Molecular Weight 310.39
Formula C₁₆H₂₆N₂O₄
SMILES

O=C(OC)NCCC1=CC=C(OCC(O)CNC(C)C)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocol

Animal Administration^[1]

Three male Sprague-Dawley rats weighing 200-250 g are given pamatolol-sulphate dissolved in water at a dose of 50 mg/kg (10 μCi/mg) by means of a stomach tube. The rats are housed in metabolic cages that allows for separate collection of urine and feces for a 24 hr period. They are given a commercial pellet diet and drinking water ad libitum.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hoffmann KJ, et al. Species differences in the metabolism of pamatolol, a cardioselective beta--adrenoceptor antagonist. Eur J Drug Metab Pharmacokinet. 1979;4(3):163-73. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- In Vivo
Chemical Information
Protocol
Purity & Documentation
References

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Pamatolol

All Adrenergic Receptor Isoforms