Protease-Activated Receptor-4
Based on 1 Customer Validation
Protease-Activated Receptor-4 is the agonist of proteinase-activated receptor-4 (PAR4).
For research use only. We do not sell to patients.
- Purity: 95.67%
- CAS No.: 245443-52-1
- Formula: C33H46N8O7
- Molecular Weight:666.77
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PAR4 |
Chemical Information
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CAS No. 245443-52-1
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Appearance Solid
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Molecular Weight 666.77
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Formula C33H46N8O7
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Color White to off-white
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Sequence
Gly-Tyr-Pro-Gly-Lys-Phe-NH2
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Sequence Shortening
GYPGKF-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 50 mg/mL (74.99 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (149.98 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Moschonas IC, et al. Molecular requirements involving the human platelet protease-activated receptor-4 mechanism of activation by peptide analogues of its tethered-ligand. Platelets. 2017 Mar 7:1-10. doi: 10.1080/09537104.2017.1282607. [Epub ahead of print] [Content Brief]
[2]. Huang SC, et al. Proteinase-activated receptor-1 (PAR1) and PAR2 mediate relaxation of guinea pig internal anal sphincter. Regul Pept. 2014 Feb 10;189:46-50. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.4998 mL | 7.4988 mL | 14.9977 mL | 37.4942 mL |
| 5 mM | 0.3000 mL | 1.4998 mL | 2.9995 mL | 7.4988 mL | |
| 10 mM | 0.1500 mL | 0.7499 mL | 1.4998 mL | 3.7494 mL | |
| 15 mM | 0.1000 mL | 0.4999 mL | 0.9998 mL | 2.4996 mL | |
| 20 mM | 0.0750 mL | 0.3749 mL | 0.7499 mL | 1.8747 mL | |
| 25 mM | 0.0600 mL | 0.3000 mL | 0.5999 mL | 1.4998 mL | |
| 30 mM | 0.0500 mL | 0.2500 mL | 0.4999 mL | 1.2498 mL | |
| 40 mM | 0.0375 mL | 0.1875 mL | 0.3749 mL | 0.9374 mL | |
| 50 mM | 0.0300 mL | 0.1500 mL | 0.3000 mL | 0.7499 mL | |
| 60 mM | 0.0250 mL | 0.1250 mL | 0.2500 mL | 0.6249 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Protease-Activated Receptor-4 Related Classifications
HY-P0297 Related Classifications
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