1. MAPK/ERK Pathway
    Autophagy
    Immunology/Inflammation
    NF-κB
    Metabolic Enzyme/Protease
  2. Ribosomal S6 Kinase (RSK)
    Autophagy
    Reactive Oxygen Species
  3. Quercitrin

Quercitrin (Synonyms: Quercetin 3-rhamnoside)

Cat. No.: HY-N0418 Purity: 99.12%
Handling Instructions

Quercitrin is a natural compound found in Tartary buckwheat with a potential anti-inflammation effect that is used to treat heart and vascular conditions.

For research use only. We do not sell to patients.

Quercitrin Chemical Structure

Quercitrin Chemical Structure

CAS No. : 522-12-3

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
5 mg USD 60 In-stock
Estimated Time of Arrival: December 31
10 mg USD 84 In-stock
Estimated Time of Arrival: December 31
50 mg USD 180 In-stock
Estimated Time of Arrival: December 31
100 mg USD 312 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Quercitrin is a natural compound found in Tartary buckwheat with a potential anti-inflammation effect that is used to treat heart and vascular conditions. IC50 value: Target: In vitro: There were significant increases in caspase-3 activity, loss of MMP, and increases in the apoptotic cell population in response to quercitrin in DLD-1 colon cancer cells in a time- and dose-dependent manner. [1] In vivo: ICR mice received CCl4 intraperitoneally with or without quercitrin co-administration for 4 weeks. Data showed that quercitrin significantly suppressed the elevation of reactive oxygen species (ROS) production and malondialdehyde (MDA) content, reduced tissue plasminogen activator (t-PA) activity, enhanced the antioxidant enzyme activities and abrogated cytochrome P450 2E1 (CYP2E1) induction in mouse brains. [2]

Molecular Weight

448.38

Formula

C₂₁H₂₀O₁₁

CAS No.

522-12-3

SMILES

OC1=CC(O)=C(C(C(O[[email protected]]2[[email protected]](O)[[email protected]](O)[[email protected]@H](O)[[email protected]](C)O2)=C(C3=CC(O)=C(O)C=C3)O4)=O)C4=C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 31 mg/mL (69.14 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2303 mL 11.1513 mL 22.3025 mL
5 mM 0.4461 mL 2.2303 mL 4.4605 mL
10 mM 0.2230 mL 1.1151 mL 2.2303 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.58 mg/mL (5.75 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.58 mg/mL (5.75 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
Quercitrin
Cat. No.:
HY-N0418
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