2. MAPK/ERK Pathway Apoptosis Autophagy Metabolic Enzyme/Protease Immunology/Inflammation NF-κB
  3. Ribosomal S6 Kinase (RSK) Apoptosis Autophagy Reactive Oxygen Species
  4. Quercitrin

Quercitrin  (Synonyms: Quercetin 3-rhamnoside)

Cat. No.: HY-N0418 Purity: 99.80%
COA Handling Instructions

Quercitrin (Quercetin 3-rhamnoside) is a bioflavonoid compound with potential anti-inflammation, antioxidative and neuroprotective effect. Quercitrin induces apoptosis of colon cancer cells. Quercitrin can be used for the research of cardiovascular and neurological disease research.

For research use only. We do not sell to patients.

Quercitrin Chemical Structure

Quercitrin Chemical Structure

CAS No. : 522-12-3

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 33 In-stock
Solution
10 mM * 1 mL in DMSO USD 33 In-stock
Solid
5 mg USD 30 In-stock
10 mg USD 50 In-stock
50 mg USD 150 In-stock
100 mg USD 250 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Quercitrin Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Quercitrin

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Quercitrin (Quercetin 3-rhamnoside) is a bioflavonoid compound with potential anti-inflammation, antioxidative and neuroprotective effect. Quercitrin induces apoptosis of colon cancer cells. Quercitrin can be used for the research of cardiovascular and neurological disease research[1][2].

In Vitro

Quercitrin (5-50 μM; 24-72 h) time- and dose-dependently inhibits cell proliferation and increases cytotoxic effects to colorectal carcinoma cells[1].
Quercitrin (5-50 μM; 24-72 h) time- and dose-dependently increases nucleosomal enrichment factor (EF) of DLD-1 cells[1].
Quercitrin (50 μM; 48-72 h) induces cell apoptosis and the loss of mitochondrial membrane potential, and causes translocation of phosphatidylserine (PS) from the inner to outer Leaflet of DLD-1 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Quercitrin Related Antibodies

Cell Proliferation Assay[1]

Cell Line: DLD-1 colon cancer cell lines
Concentration: 5, 10, 25 and 50 μM
Incubation Time: 24, 48 and 72 hours
Result: Time- and Dose-dependently decreased cell proliferation of colorectal carcinoma cells.

Apoptosis Analysis[1]

Cell Line: DLD-1 colon cancer cell lines
Concentration: 50 μM
Incubation Time: 48 and 72 hours
Result: Induced cell apoptosis and time- and dose-dependently increased caspase-3 enzyme activity.
In Vivo

Quercitrin (50 and 100 mg/kg; oral gavage, once) shows effective protection against brain injury in mice by inhibiting oxidative stress and inflammation induced by carbon tetrachloride[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male ICR mice with carbon tetrachloride (CCl4) induced brain injury[2]
Dosage: 50 and 100 mg/kg
Administration: Oral gavage; 50 and 100 mg/kg, once
Result: Dose-dependently decreased the levels of ROS and malondialdehyde (MDA) concentration in the hippocampus homogenates, and also dose-dependently decreased the CYP2E1 level in the brains. Increased the activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx). Inhibited the N-methyl-D-aspartate receptor 2B subunit (NR2B) level and the activities of monoamine oxidase (MAO) and acetylcholine esterase (AChE) in mouse brains.
Molecular Weight

448.38

Appearance

Solid

Formula

C21H20O11
CAS No.
SMILES

OC1=CC(O)=C(C(C(O[C@H]2[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O2)=C(C3=CC(O)=C(O)C=C3)O4)=O)C4=C1
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (278.78 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2303 mL 11.1513 mL 22.3025 mL
5 mM 0.4461 mL 2.2303 mL 4.4605 mL
10 mM 0.2230 mL 1.1151 mL 2.2303 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.58 mg/mL (5.75 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.08 mg/mL (4.64 mM); Clear solution

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation

Purity: 99.80%

COA (257 KB) HNMR (306 KB) LCMS (268 KB)

Handling Instructions (2659 KB)
References
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Quercitrin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Quercitrin522-12-3Quercetin 3-rhamnosideRibosomal S6 Kinase (RSK)ApoptosisAutophagyReactive Oxygen SpeciesS6Kcolon cancerquercitrinantiproliferativeapoptosisanti-inflammationneuroprotectiveInhibitorinhibitorinhibit

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