1. Anti-infection
  2. Influenza Virus

RO-7 

Cat. No.: HY-112684
Handling Instructions

RO-7 is a next-generation polymerase (PA) endonuclease inhibitor of influenza A and B viruses.

For research use only. We do not sell to patients.

RO-7 Chemical Structure

RO-7 Chemical Structure

CAS No. : 1370241-45-4

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

RO-7 is a next-generation polymerase (PA) endonuclease inhibitor of influenza A and B viruses.

In Vitro

RO-7 is a compound that potently inhibits influenza virus replication and belongs to a new class of drugs in late-stage clinical trials for treatment of influenza virus infection. RO-7 displays broad-spectrum anti-influenza activity in vitro and protects mice from lethal challenge with both influenza A and B viruses[1].

In Vivo

RO-7 protects mice from lethal challenge with both influenza A and B viruses[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0513 mL 10.2566 mL 20.5132 mL
5 mM 0.4103 mL 2.0513 mL 4.1026 mL
10 mM 0.2051 mL 1.0257 mL 2.0513 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

487.49

Formula

C₂₄H₂₀F₃N₃O₃S

CAS No.

1370241-45-4

SMILES

O=C1N([[email protected]](C)C(F)(F)F)CN([[email protected]@H]2C3=CC=CC=C3SCC4=CC=CC=C24)N5C1=C(O)C(C=C5)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
RO-7
Cat. No.:
HY-112684
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RO-7

Cat. No.: HY-112684