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Art. -Nr.: HY-U00072

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RS-601

Name: RS-601
Brand: MedChemExpress
SKU: HY-U00072
Price: 1347.00 USD
Availability: InStock
Rating: 5 (1 reviews)

RS-601 is a novel leukotriene D4 (LTD4)/thromboxane A2 (TxA2) dual receptor antagonist, with antiasthmatic activities.

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CAS. Nr.: 207987-59-5
Formel: C₂₂H₂₃F₆NO₄S
Molecular Weight:511.48

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

RS-601 Chemical Structure

CAS. Nr.: 207987-59-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vivo
Chemical Information
Reinheit & Dokumentation
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Calculators
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Biologische Aktivität

Beschreibung

RS-601 is a novel leukotriene D4 (LTD4)/thromboxane A2 (TxA2) dual receptor antagonist, with antiasthmatic activities.

IC₅₀ & Target^[1]

LTD₄	TXA₂ Receptor

Alle Leukotriene Receptor Isoform-spezifische Produkte anzeigen :

Alle Prostaglandin Receptor Isoform-spezifische Produkte anzeigen :

In Vivo

RS-601 (1-10 mg/kg) clearly inhibits the bronchoconstriction induced by intravenous administration of U-46619 and LTD4 in a dose-dependent fashion in guinea pigs. RS-1452 (10 mg/kg) significantly inhibits U-46619-induced bronchoconstriction, respectively. RS-601 significantly inhibits the late-phase response and LPS-induced AHR at a dose of 10 mg/kg, but does not affect biphasic bronchial responses. RS-601 (3 and 10 mg/kg) also clearly inhibits the AHR^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 207987-59-5
Molecular Weight 511.48
Formel C₂₂H₂₃F₆NO₄S
SMILES

O=C(O)CCCC1=CC=C(C(NS(=O)(C2=CC=C(F)C=C2)=O)CCCC(F)(F)C(F)(F)F)C=C1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Yamada T, et al. Effects of RS-601, a novel leukotriene D(4)/thromboxane A(2) dual receptor antagonist, on asthmatic responses in guinea pigs. Pharmacology. 2003 Sep;69(1):51-8. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vivo
Chemical Information
Reinheit & Dokumentation
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RS-601

KP496

Montelukast sodium

Etalocib

LY255283

Masilukast

YM158 free base

SR2640 hydrochloride

ONO4057

Ablukast

Bunaprolast

Etalocib (Standard)

Montelukast sodium (Standard)

Alle Leukotriene Receptor Isoform-spezifische Produkte anzeigen

Alle Prostaglandin Receptor Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Bioz

RS-601

KP496

Montelukast sodium

Etalocib

LY255283

Masilukast

YM158 free base

SR2640 hydrochloride

ONO4057

Ablukast

Bunaprolast

Etalocib (Standard)

Montelukast sodium (Standard)

Alle Leukotriene Receptor Isoform-spezifische Produkte anzeigen

Alle Prostaglandin Receptor Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

RS-601 Related Classifications

HY-U00072 Related Classifications

Bioz