1. GPCR/G Protein
  2. Leukotriene Receptor
    Prostaglandin Receptor
  3. RS-601

RS-601 

Cat. No.: HY-U00072
Handling Instructions

RS-601 is a novel leukotriene D4 (LTD4)/thromboxane A2 (TxA2) dual receptor antagonist, with antiasthmatic activities.

For research use only. We do not sell to patients.

RS-601 Chemical Structure

RS-601 Chemical Structure

CAS No. : 207987-59-5

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Description

RS-601 is a novel leukotriene D4 (LTD4)/thromboxane A2 (TxA2) dual receptor antagonist, with antiasthmatic activities.

IC50 & Target[1]

LTD4

 

TXA2 Receptor

 

In Vivo

RS-601 (1-10 mg/kg) clearly inhibits the bronchoconstriction induced by intravenous administration of U-46619 and LTD4 in a dose-dependent fashion in guinea pigs. RS-1452 (10 mg/kg) significantly inhibits U-46619-induced bronchoconstriction, respectively. RS-601 significantly inhibits the late-phase response and LPS-induced AHR at a dose of 10 mg/kg, but does not affect biphasic bronchial responses. RS-601 (3 and 10 mg/kg) also clearly inhibits the AHR[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

511.48

Formula

C₂₂H₂₃F₆NO₄S

CAS No.

207987-59-5

SMILES

O=C(O)CCCC1=CC=C(C(NS(=O)(C2=CC=C(F)C=C2)=O)CCCC(F)(F)C(F)(F)F)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

RS-601RS601RS 601Leukotriene ReceptorProstaglandin ReceptorInhibitorinhibitorinhibit

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RS-601
Cat. No.:
HY-U00072
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