Infection

Gentamicin C2 is an aminoglycoside antibiotic with broad-spectrum bactericidal activity, selectively binding to the bacterial 16S rRNA A-site. Gentamicin C2 interferes with protein synthesis initiation and translation fidelity to exert bactericidal effects. Gentamicin C2 can be used for the research of bacterial infections.

Antibacterial agent 328 is a enoyl-ACP reductase (InhA) inhibitor and antimycobacterial agent. Antibacterial agent 328 blocks mycolic acid biosynthesis in Mycobacterium tuberculosis. Antibacterial agent 328 acts on both drug-resistant and drug-susceptible Mycobacterium tuberculosis strains. Antibacterial agent 328 exhibits favorable pharmacokinetic properties, drug-likeness, and a safety-related selectivity index. Antibacterial agent 328 can be used for research on tuberculosis.

Promothiocin B is an antibiotic. The minimum induction concentration of Promothiocin B for tipA promoter is 0.1 μg/mL.

DDHF20 is an antimicrobial agent against Staphylococcus aureus, targeting and inhibiting its thioredoxin reductase (TrxR). It acts as a competitive inhibitor for the NADPH binding site. DDHF20 is expected to be used in research related to antimicrobial infections caused by Staphylococcus aureus.

Piperazinomycin is an antifungal and antibacterial antibiotic. Piperazinomycin is isolated from the culture broth of Streptoverticillium olivoreticuli subsp. neoenacticus. Piperazinomycin inhibits the growth of fungi, yeasts and some Mycobacterium species. Piperazinomycin exhibits inhibitory activity against Trichophyton species.

Pyraflufen is a pyrazolylphenyl herbicide that can be used for selective control of broadleaf weeds. Pyraflufen can inhibit plant enzyme protoporphyrinogen oxidase.

Cyanosafracin B (Standard) is the analytical standard of Cyanosafracin B (HY-137787). This product is intended for research and analytical applications. Cyanosafracin B is an Antibiotic. Cyanosafracin B is present in the fermentation products of Pseudomonas fluorescens. Cyanosafracin B can be used for the synthesis of Ecteinascidin.

Diaporthin is a phytotoxin that can be isolated from Cryphonectria parasitica. Diaporthin possesses antimicrobial activity in bacteria.

4,5-Dihydropiperlonguminine is a natural product that can be isolated from the seeds of Piper tuberculatum Jacq. (Piperaceae). 4,5-Dihydropiperlonguminine is a insecticide against velvetbean caterpillars.

9-Methylguanine, a derivative of 8-mercaptoguanine, is a dihydropteroate synthase (DHPS) inhibitor with a K_d of 58 μM for E.coli DHPS (EcDHPS).

Napyradiomycin C1 is an antibiotic with anti-Gram-positive bacteria and mycobacterial activity. Napyradiomycin C1 almost none to Gram-negative bacteria and fungi. IC₅₀ (μg/mL) of leukemia L-1210 cells is 9.2.

YM-53601 (Standard) is the analytical standard of YM-53601 (HY-100313A). This product is intended for research and analytical applications. YM-53601, a squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in vivo. YM-53601 inhibits squalene synthase derived from human hepatoma cells with an IC50 of 79 nM. Lipid-lowering agent. YM-53601 is also an inhibitor of farnesyl-diphosphate farnesyltransferase 1 (FDFT1) enzyme activity and abrogates HCV propagation.

Fantofarone (Standard) is the analytical standard of Fantofarone. This product is intended for research and analytical applications. Fantofarone is a highly potent Calcium Channel antagonist.

Nectrisine is a competitive, targeted α-glucosidase inhibitor with an IC₅₀ of 29 μM. Nectrisine also exhibits varying degrees of inhibitory activity against rat trimming glucosidase I, jack bean α-mannosidase, almond β-glucosidase, snail β-mannosidase, and bovine β-N-acetylglucosaminidase. Nectrisine further inhibits syncytium formation and hemolytic activity in Newcastle disease virus-infected cells, and acts as an immunomodulator to induce Ia antigen expression and restore immune responses suppressed by tumor-derived immunosuppressive factors.

Mutalomycin is a polyether antibiotic. Mutalomycin has anti-Gram-positive bacteria, anti-mycoplasma and anti-coccidial activity.

Gentamicin X2 is a minor aminoglycoside antibiotic component in the gentamicin complex.

3,4'-Dihydroxyflavone (Standard) is the analytical standard of 3,4'-Dihydroxyflavone (HY-111802). This product is intended for research and analytical applications. 3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus.

alpha-Bisabolol (Standard) is the analytical standard of alpha-Bisabolol. This product is intended for research and analytical applications. alpha-Bisabolol, an orally active sesquiterpene alcohol, induces cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol exerts a protective action against Cisplatin (HY-17394)-induced nephrotoxicity by mitigating inflammation and oxidative stress through the inhibition of NFκB activation. alpha-Bisabolol exhibits anti-inflammatory, analgesic, antibiotic and anticancer activities.

SJL 01 (Compound 8) is an anti-parasitic agent. SJL 01 (Compound 8) is cytotoxic to L-6 myocytes and exhibits antileishmaniasis activity both in vivo and in vitro. SJL 01 can be used for visceral leishmaniasis research.

Azithromycin-d₅ (CP-62993-d₅) is the deuterium labeled Azithromycin (CP-62993) (HY-17506). Azithromycin is a macrolide antibiotic useful for thestudy of a number of bacterial infections.