Metabolic Disease
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Metabolic Disease Related Products (16328)
Related Products (16328)
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Antibodies (62)
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Related Compound Screening Libraries (3)
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Meglitinide
0 ImagesCat. No.: HY-15210CAS No.: 54870-28-9Meglitinide is an ATP-sensitive potassium (KATP) channel inhibitor. Meglitinide exhibits IC50 values of 0.26 μM, 0.53 μM and 1.6 μM against KATP channels containing SUR1, SUR2A and SUR2B, respectively, with a Kd value of 7 μM for both SUR1 and SUR2A, and a Kd value of 8 μM for SUR2B. Meglitinide binds to the SUR1, SUR2A and SUR2B subunits with high affinity to close KATP channels, acting on a binding site shared by all SUR subtypes, and its interaction with SUR1 carrying the S1237Y mutation remains unchanged. Meglitinide is applicable to research related to type 2 diabetes.
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N6-[N-(6-Aminohexyl)carbamoylmethyl]-CoA
![N6-[N-(6-Aminohexyl)carbamoylmethyl]-CoA](https://file.medchemexpress.com/product_pic/hy-ce01610.gif "Click to View N6-[N-(6-Aminohexyl)carbamoylmethyl]-CoA Product Detail")
0 ImagesCat. No.: HY-CE01610CAS No.: 71974-85-1Synonyms: N6-[N-(6-Aminohexyl)carbamoylmethyl]-coenzyme AN6-[N-(6-Aminohexyl)carbamoylmethyl]-CoA (N6-[N-(6-Aminohexyl)carbamoylmethyl]-coenzyme A) is a coenzyme A derivative.
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AMG-222
0 ImagesCat. No.: HY-111150CAS No.: 913978-37-7AMG-222 is a dipeptidyl peptidase IV (DPP-IV) inhibitor that exerts its inhibitory effect by tightly and reversibly binding to DPPIV. AMG 222 binds to human plasma proteins in a saturable and concentration-dependent manner, with a binding rate of 80.8% at 1 nM, while the binding rate decreases to 29.4% at concentrations above 100 nM. AMG-222 can be used in research related to diabetes.
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Choline oxidase, Arthrobacter globiformis
0 ImagesCat. No.: HY-P2743BCholine oxidase, Arthrobacter globiformis (EC 1.1.3.17) is an oxidoreductase that acts on the CH-OH group in a donor molecule and uses oxygen as an acceptor. The two substrates of Choline oxidase, Arthrobacter globiformis (EC 1.1.3.17) are choline and O2, and the two products are betaine aldehyde and H2O2.
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Emodin-1-O-β-gentiobioside
0 ImagesCat. No.: HY-N8143CAS No.: 849789-95-3Emodin-1-O-β-gentiobioside is an anthraquinone.
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GLP-1R agonist 16
0 ImagesCat. No.: HY-147629CAS No.: 2763329-13-9GLP-1R agonist 16 (Compound 115a) is a GLP-1 receptor agonist with an EC50 of 0.15 nM.
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N-Acetyl-D-glucosamine-13C6
0 ImagesCat. No.: HY-A0132S12CAS No.: 1194446-34-8Synonyms: N-Acetyl-2-amino-2-deoxy-D-glucose-13C6N-Acetyl-D-glucosamine-13C6 (N-Acetyl-2-amino-2-deoxy-D-glucose-13C6) is the 13C labled N-Acetyl-D-glucosamine (HY-A0132). N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of glucose.
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Naphthyl-2-methylene-succinyl-CoA
0 ImagesCat. No.: HY-CE01613Synonyms: Naphthyl-2-methylene-succinyl-coenzyme ANaphthyl-2-methylene-succinyl-CoA (Naphthyl-2-methylene-succinyl-coenzyme A) is a coenzyme A derivative.
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Phosphoenolpyruvate-CoA
0 ImagesCat. No.: HY-CE01731Synonyms: Phosphoenolpyruvate-coenzyme APhosphoenolpyruvate-CoA (Phosphoenolpyruvate-coenzyme A) is a coenzyme A derivative.
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Cyclohex-1-ene-1-carboxyl-CoA
0 ImagesCat. No.: HY-CE01296Synonyms: Cyclohex-1-ene-1-carboxyl-coenzyme ACyclohex-1-ene-1-carboxyl-CoA (Cyclohex-1-ene-1-carboxyl-coenzyme A) is a coenzyme A derivative.
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α-Homonojirimycin
0 ImagesCat. No.: HY-119593CAS No.: 119557-99-2Synonyms: Homonojirimycinα-Homonojirimycin is a potent α-glucosidase inhibitor.
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ICK Recombinant Human Active Protein Kinase
0 ImagesCat. No.: HY-E70729The intestinal cell kinase (ICK) protein belongs to the ros-cross hybridizing kinase (RCK) family. ICK is a ciliary protein, involved in ciliogenesis and regulation of intraflagellar transport (IFT). ICK Recombinant Human Active Protein Kinase is a recombinant ICK protein that can be used to study ICK-related functions.
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Amiloride-15N3 hydrochloride
0 ImagesCat. No.: HY-B0285ASCAS No.: 1216796-18-7Synonyms: MK-870-15N3 hydrochlorideAmiloride-15N3 (hydrochloride) is the 15N labeled Amiloride hydrochloride. Amiloride hydrochloride (MK-870 hydrochloride) is an inhibitor of both epithelial sodium channel (ENaC) and urokinase-type plasminogen activator receptor (uTPA). Amiloride hydrochloride is a blocker of polycystin-2 (PC2;TRPP2) channel.
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F 2833
0 ImagesCat. No.: HY-105961CAS No.: 107430-45-5F 2833 is a lipid-lowering agent. F 2833 can reduce the levels of cholesterol, triglycerides, and plasma phospholipids. F 2833 can be used for research on diseases such as hyperlipidemia.
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Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine
0 ImagesCat. No.: HY-P5279CAS No.: 2228114-98-3Palmitoyl dipeptide-7 is a bioactive peptide with anti-aging effects that has been reported for use as a cosmetic ingredient.
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2-Methoxy-estradiol-17beta 3-glucuronide
0 ImagesCat. No.: HY-180679CAS No.: 52718-01-12-Methoxy-estradiol-17beta 3-glucuronide is a nucleoside metabolite.
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5-HT2A&5-HT2C agonist-2
0 ImagesCat. No.: HY-1801855-HT2A&5-HT2C agonist-2 (Compound 3ci) is a highly selective dual 5-HT2A/5-HT2C agonist that can cross the blood-brain barrier and has an EC50 < 1 μM. 5-HT2A&5-HT2C agonist-2 has high selectivity for 5-HT2B related to the risk of heart valve disease. 5-HT2A&5-HT2C agonist-2 can induce head convulsive responses, but has a relatively low hallucinogenic potential. 5-HT2A&5-HT2C agonist-2 can be used in the research of diseases such as depression and obesity.
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SB-435495 ditartrate
0 ImagesCat. No.: HY-19415BCAS No.: 304694-43-7SB-435495 ditartrate is a potent, selective, reversible, non-covalent and orally active Lp-PLA2 inhibitor with an IC50 of 0.06 nM.
