1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N12325
    3,4-Dihydroxyallylbenzene 3,4-di-O-glucoside
    Inhibitor
    3,4-Dihydroxyallylbenzene 3,4-di-O-glucoside (Compound 4) is a phenylpropanoid glycoside. 3,4-Dihydroxyallylbenzene 3,4-di-O-glucoside is found in the the dragon’s blood of Dracaena cambodiana. 3,4-Dihydroxyallylbenzene 3,4-di-O-glucoside exhibits antibacterial activity.
    3,4-Dihydroxyallylbenzene 3,4-di-O-glucoside
  • HY-19246
    DZ-2640
    Inhibitor
    DZ-2640 is an orally active Carbapenem antibiotic, a prodrug of DU-6681 (HY-19247). DU-6681 exhibits antibacterial activity against a broad spectrum of gram-positive and -negative bacteria.
    DZ-2640
  • HY-178919
    N-19004
    Inhibitor
    N-19004 is a FPR1 antagonist. N-19004 shows broad-spectrum antibacterial effects against a variety of pathogens. N-19004 exhibits significant retinal protective effects in the rd10 mouse model of retinitis pigmentosa (RP). N-19004 can attenuate retinal dysfunction, mitigate rod and cone degeneration, and reduce immune cell activation, gliosis, inflammation, oxidative stress, and apoptosis. N-19004 can reduce the size of laser-induced choroidal lesions and promote edema absorption through dual anti-inflammatory and anti-angiogenic effects. N-19004 can be used for the research of retinal degenerative diseases such as retinitis pigmentosa.
    N-19004
  • HY-N19233
    Geministatin B
    Inhibitor
    Geministatin B is a potent antibiotic that can be found in the fungus Austroacremonium gemini MST-FP2131. Geministatin B exhibits antibacterial activity against Gram-positive bacteria including Bacillus subtilis, Staphylococcus aureus, and methicillin-resistant S. aureus (MRSA). Geministatin B can be used for the research of bacterial infections.
    Geministatin B
  • HY-B1431S2
    Butylparaben-d9
    Inhibitor
    Butylparaben-d9 (Butyl parahydroxybenzoate-d9; Butyl paraben-d9) is a deuterium labeled Butylparaben (HY-B1431).
    Butylparaben-d<sub>9</sub>
  • HY-105932R
    Lexithromycin (Standard)
    Inhibitor
    Lexithromycin (Standard) is the analytical standard of Lexithromycin. This product is intended for research and analytical applications. Lexithromycin is an erythromycin A derivative, with antibacterial activity.
    Lexithromycin (Standard)
  • HY-D3195
    CDr15
    CDr15 is a deep-red fluorescent probe (Ex=733 nm) that can selectively intercalate into and label bacterial extracellular DNA (eDNA). CDr15 exhibits extremely high specificity for biofilm imaging and cannot effectively bind to mammalian nuclear DNA. CDr15 enables real-time visualization of the microcolony structure and developmental process of three-dimensional *Pseudomonas aeruginosa* biofilms, and accurately localizes biofilm-forming regions of microorganisms in a mouse corneal infection model. With low background interference signals, CDr15 serves as an ideal diagnostic tool for research fields including bacterial biofilms and corneal infections.
    CDr15
  • HY-155846
    Antileishmanial agent-22
    Inhibitor
    Antileishmanial agent-22 (compound 15b) is a parasite inhibitor and an antibacterial agent, with antileishmanial, antimalarial, and anti-tubercular activities. Antileishmanial agent-22 inhibits leishmanial (IC50=0.408 μM) based on antifolate mechanism. And, Antileishmanial agent-22 inhibits Folic acid and Folinic acid at 100 μM with inhibitory rates of 88% and 94%, respectively. Antileishmanial agent-22 inhibits P. berghei in vivo and in vitro, with 96.67% suppression under 48.4 μM/kg/day and 0.038 μM (IC50), respectively. Moreover, Antileishmanial agent-22 inhibits M. tuberculosis with MIC of 28.44 μM.
    Antileishmanial agent-22
  • HY-129724
    α-MSH (11-13)
    Inhibitor
    α-MSH (11-13) (ACTH-(11-13)) is a C-terminal tripeptide of α-MSH that can cross the blood-brain barrier. α-MSH (11-13) exhibits antipyretic, anti-inflammatory, and antibacterial activities. α-MSH (11-13) also exerts neuroprotective effects after traumatic brain injury by inhibiting excessive activation of microglia and reducing neuronal apoptosis. α-MSH (11-13) can be used in research related to traumatic brain injury, fever, and bacterial infections.
    α-MSH (11-13)
  • HY-N0717S8
    L-Valine-d1
    Inhibitor 98.0%
    L-Valine-d1 ((S)-Valine-d1) is the deuterium labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase.
    L-Valine-d<sub>1</sub>
  • HY-147944
    Antimicrobial agent-4
    Inhibitor
    Antimicrobial agent-4 (compound 6a) is a potent antimicrobial agent. Antimicrobial agent-4 exhibits considerable activity against the microbial pathogens. Antimicrobial agent-4 delivers reliable toxicity to kill the bacteria and fungi. Antimicrobial agent-4 shows high binding energy value of −10.0 kcal/mole against the target enzyme.
    Antimicrobial agent-4
  • HY-A0256R
    Clavulanic acid (Standard)
    Inhibitor
    Clavulanic acid (Standard) is the analytical standard of Clavulanic acid. This product is intended for research and analytical applications. Clavulanic acid is a naturally occurring powerful bacterial β-lactamases inhibitor for research of infections caused by bacteria, including infections of the ears. Clavulanic acid is active against a wide spectrum of gram-positive and gram-negative bacterias[1].
    Clavulanic acid (Standard)
  • HY-178722
    Deferasirox methyl ester
    Inhibitor 98.40%
    Deferasirox methyl ester (compound 6a), a derivative of Deferasirox (HY-17359), is an antimicrobial agent. Deferasirox methyl ester exhibits activities against Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Candida albicans and Aspergillus niger with MICs of 0.5, 4.0, 1.0, 4.0, and 2.0 μg/mL, respectively. Deferasirox methyl ester can be used for antimicrobial research.
    Deferasirox methyl ester
  • HY-N11685
    (±)-Lomatin
    Inhibitor
    (±)-Lomatin (Xanthogalol) (Compound 10) is a coumarin-type secondary metabolite. (±)-Lomatin can be found in Coleonema album. (±)-Lomatin can be used for the research of bacterial infections, mycobacterial infections, and fungal infections.
    (±)-Lomatin
  • HY-130052
    Rosellichalasin
    Inhibitor
    Rosellichalasin is an antibacterial agent isolated from the endophytic fungus Aspergillus flavipes Y-62. Rosellichalasin exhibits antibacterial activity.
    Rosellichalasin
  • HY-N0295R
    Protocatechualdehyde (Standard)
    Inhibitor
    Protocatechualdehyde (Standard) is the analytical standard of Protocatechualdehyde. This product is intended for research and analytical applications. Protocatechualdehyde (Catechaldehyde), a natural polyphenol compound isolated from the roots of radix Salviae Miltiorrhizae, is associated with a wide variety of biological activities and has been widely used in medicine as an antioxidant, anti-aging, an antibacterial and anti-inflammatory agent.
    Protocatechualdehyde (Standard)
  • HY-145325
    Antibacterial agent 66
    Inhibitor
    Antibacterial agent 66 (Compound 6q), a trifluoromethylpyridine 1,3,4-oxadiazole derivative, shows activity against Xanthomonas oryzae pv. oryzae (Xoo) with an EC50 value of 7.2 μg/mL.
    Antibacterial agent 66
  • HY-B0656AS2
    Rabeprazole-d4 potassium
    Rabeprazole-d4 potassium is deuterated labeled Rabeprazole potassium. Rabeprazole (LY307640) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole induces apoptosis. Rabeprazole acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an b>IC50 of 0.3 μM. Rabeprazole can be used for the research of gastric ulcerations and gastroesophageal reflux.
    Rabeprazole-d<sub>4</sub> potassium
  • HY-N18650
    Raphanus sativus extract
    Raphanus sativus extract, derived from the radish plant, possesses detoxifying, anti-inflammatory, antioxidant, and antibacterial properties. Its main bioactive components include glucosinolates, anthocyanins, flavonoids, and vitamin C.
    Raphanus sativus extract
  • HY-139767
    Antibacterial agent 50
    Inhibitor
    Antibacterial agent 50 (example 47) is an antibacterial agent with MIC values of 32 mcg/mL, 64 mcg/mL, and 128 mcg/mL against E. coli strains NCTC 13351, M 50 and 7 MP, respectively (WO2013030733A1).
    Antibacterial agent 50
Cat. No. Product Name / Synonyms Application Reactivity