2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. CDK
  5. CDK2 Isoform
  6. CDK2 Antagonist

CDK2 Antagonist

CDK2 Antagonist (1):

Cat. No. Product Name Effect Purity
  • HY-108136A
    Bisindolylmaleimide X hydrochloride
    		Antagonist 98.90%
    Bisindolylmaleimide X hydrochloride(Ro 31-8425 hydrochloride, BIM-X hydrochloride) is a cell-penetrating PKC inhibitor. Bisindolylmaleimide X hydrochloride is a potent cyclin-dependent kinase 2 (CDK2) antagonist with an IC50 of 200 nM. Bisindolylmaleimide X hydrochloride inhibits the proliferation of CD4 T cells in vitro. Bisindolylmaleimide X hydrochloride inhibits eNOS-Ser1177 phosphorylation in human embryonic vein endothelial cells. Bisindolylmaleimide X hydrochloride can be used for research on the immune system and cardiovascular diseases.