Dopamine Transporter Modulator
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SRI-29574
0 ImagesArt. -Nr.: HY-126158CAS. Nr.: 1928712-46-2SRI-29574 is an allosteric modulator of the dopamine transporter (DAT). SRI-29574 partially inhibits the uptake of the DAT (IC50=2.3 nM) and also partially inhibits the uptake of the serotonin transporter (SERT) and norepinephrine transporter (NET). SRI-29574 may serve as a useful probe to study the function and regulatory mechanisms of DAT.
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SRI-32743
0 ImagesArt. -Nr.: HY-175535CAS. Nr.: 1940118-42-2SRI-32743 is an allosteric human dopamine transporter (hDAT) modulator (IC50=9.86 μM). SRI-32743 is promising for research of HIV-Tat-induced neurotoxicity.
