2. Signaling Pathways
  3. GPCR/G Protein
  4. G protein-coupled Bile Acid Receptor 1
  5. G protein-coupled Bile Acid Receptor 1 Ligand

G protein-coupled Bile Acid Receptor 1 Ligand

G protein-coupled Bile Acid Receptor 1 Ligands (2):

Cat. No. Product Name Effect Purity
  • HY-P5084
    Neuromedin S (human)
    		Ligand
    Neuromedin S (human) is a neuropeptide that contains 33 amino acids. Neuromedin S (human)has been identified in the brain as an endogenous ligand for the orphan G-protein coupled receptor (GPCR) FM-4/TGR-1 and acts on the neuromedin U (NMU) receptor 2 (NMUR2) in the regulation of body weight homeostasis.
  • HY-101008
    3-MPPI
    		Ligand
    3-MPPI (compound RN5) is a GPCR ligand with high selectivity for α1-adrenergic receptor, with a Ki value of 0.21 nM for α1-adrenergic receptor and 50 nM for 5-HT1A receptor. 3-MPPI modulates the α1-adrenergic receptor signaling cascade. 3-MPPI is applicable to research related to hypertension, stress-induced anxiety-like behavioral responses, and levodopa-induced dyskinesia.