1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Indoleamine 2,3-Dioxygenase (IDO)
  4. IDO1 Isoform

IDO1

 

IDO1 Related Products (26):

Cat. No. Product Name Effect Purity
  • HY-15689
    Epacadostat
    Inhibitor 99.66%
    Epacadostat (INCB 024360) is a potent and selective indoleamine 2,3-dioxigenase 1 (IDO1) inhibitor with an IC50 of 71.8 nM.
  • HY-101560
    Linrodostat
    Inhibitor 99.89%
    Linrodostat (BMS-986205) is a selective and irreversible indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC50 value of 1.1 nM in IDO1-HEK293 cells.
  • HY-N0110
    Palmatine chloride
    Inhibitor 99.49%
    Palmatine chloride is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC50s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively.
  • HY-13983
    IDO-IN-7
    Inhibitor 99.98%
    IDO-IN-7 (NLG-919 analogue) is a a potent IDO1 inhibitor with an IC50 of 38 nM.
  • HY-101111
    PF-06840003
    Inhibitor 99.95%
    PF-06840003 (EOS200271) is a highly selective orally bioavailable IDO-1 inhibitor with IC50s of 0.41 μM, 0.59 μM, and 1.5 μM for hIDO-1, dIDO-1, and mIDO-1, respectively.
  • HY-148383
    DP00477
    Inhibitor 99.03%
    DP00477 is a potent IDO1 (indoleamine 2,3-dioxygenase 1) inhibitor with an IC50 value of 7.0 µM.
  • HY-N0110B
    Palmatine hydroxide
    Inhibitor 99.64%
    Palmatine hydroxide is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC50s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively.
  • HY-D0033
    Roxyl-9
    Inhibitor 99.22%
    Roxyl-9 is a IDO1 (Indoleamine 2,3-dioxygenase 1) inhibitor.
  • HY-111540
    IDO1-IN-5
    Inhibitor 99.54%
    IDO1-IN-5 is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.
  • HY-131911
    PROTAC IDO1 Degrader-1
    Inhibitor 98.17%
    PROTAC IDO1 Degrader-1 is the first potent IDO1 (indoleamine 2,3-dioxygenase 1) degrader that hijacks IDO1 to Cereblon E3 ligase to introduce IDO1 into UPS and eventually achieve ubiquitination and degradation (DC50=2.84 μM).
  • HY-18769
    BMS-978587
    Inhibitor 99.40%
    BMS-978587 (IDO-IN-4) is an indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor, extracted from patent WO2014150677A1, Compound example 1 enantiomer 1.
  • HY-139204
    BMS-986242
    Inhibitor 99.42%
    BMS-986242 is an orally active, potent and selective indoleamine-2,3-dioxygenase 1 (IDO1) inhibitor.
  • HY-N0110A
    Palmatine
    Inhibitor
    Palmatine is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC50s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively.
  • HY-112147
    IDO1 and HDAC1 Inhibitor
    Inhibitor
    IDO1 and HDAC1 Inhibitor (Compound 10) is a dual IDO1 and HDAC1 inhibitor with IC50s of 69.0 nM and 66.5 nM, respectively.
  • HY-145280
    IDO1/2-IN-1
    Inhibitor
    IDO1/2-IN-1 (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively.
  • HY-130607
    IDO1-IN-2
    Inhibitor
    IDO1-IN-2 (compound 16) is a potent and selective IDO1 inhibitor with IC50s of 81 nM, 59 nM (mouse) and 28 nM (rat), respectively.
  • HY-144468
    IDO1-IN-17
    Inhibitor
    IDO1-IN-17 (I-4) is an IDO1 inhibitor, with an IC50 of 0.44 μM in hela cells.
  • HY-147772
    ZC0101
    Inhibitor
    ZC0101 is a potent, orally active IDO1 and TrxR dual inhibitor with IC50 values of 0.084 μM and 7.98 μM, respectively.
  • HY-151093
    IDO2-IN-1
    Inhibitor 98.86%
    IDO2-IN-1 is an orally active and potent Indoleamine 2,3-dioxygenase 2 (IDO2) inhibitor with an IC50 value of 112 nM.
  • HY-144273
    IDO1-IN-13
    Inhibitor
    IDO1-IN-13 (compound 27a) is a potent IDO1 inhibitor with an IC50 of 61.6 nM.