2. Signaling Pathways
  3. Cytoskeleton
  4. Integrin
  5. αvβ1 Isoform
  6. αvβ1 Inhibitor

αvβ1 Inhibitor

αvβ1 Inhibitor (1):

Cat. No. Product Name Effect Purity
  • HY-137561
    Bexotegrast
    		Inhibitor 98.09%
    Bexotegrast (PLN-74809) is an orally active, potent dual αvβ6/αvβ1 integrin inhibitor with Kd of 5.7 nM and 3.4 nM, respectively. Bexotegrast inhibits αvβ6- and αvβ1-induced TGF-β activation with IC50 values of 29.8 nM and 19.2 nM, respectively. Bexotegrast has antifibrogenic effects and block multiple avenues of TGF-β activation in the fibrotic lung.