Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11091)
Related Products (11091)
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(E)-Fenpyroximate-d9
0 ImagesCat. No.: HY-W758734(E)-Fenpyroximate-d9 is the deuterium labeled (E)-Fenpyroximate.
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N1-(4-Nitrophenyl)sulfanilamide-d4
0 ImagesCat. No.: HY-W191560SPurity: 98.0%Synonyms: 4-Amino-N-(4-nitrophenyl)benzenesulfonamide-d4N1-(4-Nitrophenyl)sulfanilamide-d4 is the deuterium labeled N1-(4-Nitrophenyl)sulfanilamide.
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CYP51-IN-23-d3
0 ImagesCat. No.: HY-174353SCYP51-IN-23-d3 is a potent and broad-spectrum CYP51 inhibitor with a MIC80 of 1 μg/mL against Aspergillus fumigatum. CYP51-IN-23-d3 can prevent fungal phase transformation and biofilm formation. CYP51-IN-23-d3 exhibits anti-drug resistance activity and fungal activity, and shows excellent safety for cells and significant pharmacological activity in mice. CYP51-IN-23-d3 can be used for the study of invasive fungal infections (IFIs).
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Cilostazol-d6
0 ImagesCat. No.: HY-17464S3CAS No.: 1246641-05-3Synonyms: OPC 13013-d6Cilostazol-d6 (OPC 13013-d6) is deuterium labeled Cilostazol. Cilostazol (OPC 13013) is a potent and selective inhibitor of phosphodiesterase (PDE) 3A, the isoform of PDE 3 in the cardiovascular system, with an IC50 of 0.2 μM.
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Aderbasib-d3
0 ImagesCat. No.: HY-W703549Synonyms: INCB007839-d3; INCB7839-d3Aderbasib-d3 (INCB007839-d3) is deuterium labeled Aderbasib. Aderbasib (INCB007839) is a potent, orally active and target specific low nanomolar hydroxamate-based inhibitor of ADAM10 and ADAM17. Aderbasib exhibits robust antineoplastic activity and can be used for cancer research, including diffuse large B-cell non-Hodgkin lymphoma, HER2+?breast cancer, gliomas, et al.
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Fenbufen-d9
0 ImagesCat. No.: HY-B1138SCAS No.: 1189940-96-2Fenbufen-d9 (CL-82204-d9) is the deuterium labeled Fenbufen. Fenbufen (CL-82204) is an orally active non-steroidal anti-inflammatory drug (NSAID), with antipyretic effects. Fenbufen has potent activity in a variety of animal model, including carageenin edema, UV erythema and adjuvant arthritis. Fenbufen has inhibitory activities against COX-1 and COX-2 with IC50s of 3.9 μM and 8.1 μM, respectively. Fenbufen is a caspases (caspase-1, 3, 4, 5, 9) inhibitor.
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(+)-Longifolene-13,d2
0 ImagesCat. No.: HY-N6662S(+)-Longifolene-13C,d2 is the 13C- and deuterium labeled (+)-Longifolene (HY-N6662). (+)-Longifolene is a sesquiterpenoid and a metabolite in rabbits. (+)-Longifolen is converted to primary, secondary or tertiary alcohols in rabbits, among which the primary alcohol is predominant.
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Hippuric acid-13C6
0 ImagesSynonyms: Benzoylglycine-13C6Hippuric acid-13C6 (Benzoylglycine-13C6) is 13C labeled Hippuric acid. Hippuric Acid is an orally active metabolite. Hippuric Acid can be produced by intestinal microorganisms from the metabolism of polyphenols, benzoic acid. Hippuric Acid decreases NRF2, MMP9 and leads to ROS accumulation. Hippuric Acid activates TGFβ/SMAD signaling. Hippuric Acid improves hyperuricemia and colitis. Hippuric Acid can also be used in cardiovascular disease research. .
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4-Oxofenretinide-d4
0 ImagesCat. No.: HY-109583SCAS No.: 2991099-34-2Synonyms: 4-Oxo-4-HPR-d44-Oxofenretinide-d4 (4-Oxo-4-HPR-d4) is deuterium labeled 4-Oxofenretinide. 4-Oxofenretinide (4-Oxo-4-HPR) is a metabolite of Fenretinide (HY-15373). 4-Oxofenretinide induces cell growth inhibition in ovarian, breast, and neuroblastoma tumor cell lines. 4-Oxofenretinide causes a marked accumulation of cells in G2-M. 4-Oxofenretinide induces cancer cell apoptosis through caspase-9.
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Vortioxetine-d6
0 ImagesCat. No.: HY-15414S1CAS No.: 1629684-23-6Synonyms: Lu AA 21004-d6Vortioxetine-d6 (Lu AA 21004-d6) is the deuterium labeled Vortioxetine (HY-B1490A). Vortioxetine (Lu AA 21004) is an antagonist of 5-HT3A and 5-HT7 receptors (Ki: 3.7 nM, 19 nM) and an inhibitor of serotonin transporter (SERT) (Ki: 1.6 nM), as well as a 5-HT1A agonist and a partial agonist of 5-HT1B (Ki: 15 nM, 33 nM).
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Tristearin-d9
0 ImagesTristearin-d9 is the deuterium labeled Tristearin (HY-127035). Tristearin is a triglyceride derived from three units of stearic acid.
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(±)-1-Amino-2-phenylpropane-1,1,3,3,3-d5 hydrochloride
0 ImagesCat. No.: HY-W005394S(±)-1-Amino-2-phenylpropane-1,1,3,3,3-d5 (hydrochloride) is the deuterium labeled 2-Phenylpropan-1-amine hydrochloride.
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Methyl 2-hydroxybenzoate-d3
0 ImagesCat. No.: HY-W712501CAS No.: 1335435-40-9Methyl-d3 2-hydroxybenzoate is deuterated labeled Methyl 2-hydroxybenzoate.
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PD-166285-d4
0 ImagesCat. No.: HY-132559SCAS No.: 1246814-59-4PD-166285-d4 is the deuterium labeled PD-166285.
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(R)-Norfluoxetine phthalimide-d5
0 ImagesCat. No.: HY-133171AS1CAS No.: 1346617-46-6(R)-Norfluoxetine-d5 Phthalimide (Phenyl-d5) is the deuterium labeled (R)-Norfluoxetine Phthalimide (Phenyl).
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2-Hydroxycinnamic acid-d4
0 ImagesCat. No.: HY-W012531S22-Hydroxycinnamic acid-d4 is deuterium labeled 2-Hydroxycinnamic acid. 2-Hydroxycinnamic acid is a phenolic acid with antimicrobial and antioxidant properties. 2-Hydroxycinnamic acid has antimicrobial activity against Staphylococcus aureus and is not susceptible to drug resistance. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 0.3 mM. In addition, 2-Hydroxycinnamic acid has neuroprotective and antitumor activity.
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5-Octyldihydrofuran-2(3H)-one-d7
0 ImagesCat. No.: HY-W275481S2CAS No.: 1104979-35-2Synonyms: γ-Laurolactone-d75-Octyldihydrofuran-2(3H)-one-d7 is deuterated labeled 5-Octyldihydrofuran-2(3H)-one.
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Acotiamide-d4
0 ImagesCat. No.: HY-121467S1Synonyms: Z-338 free base-d4; YM443 free base-d4Acotiamide-d4 (Z-338 (free base)-d4) is deuterium labeled Acotiamide. Acotiamide is an orally active, selective and reversible acetylcholinesterase (AChE) inhibitor, with an IC50 of 1.79 μM. Acotiamide can enhance gastric contractility and accelerate delayed gastric emptying. Acotiamide has the potential for the research of functional dyspepsia involving gastric motility dysfunction and intestinal inflammatory.
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Lisinopril-13C5,15N
0 ImagesCat. No.: HY-18206S2Synonyms: MK-521-13C5,15NLisinopril-13C5,15N (MK-521-13C5,15N) is 13C and 15N labeled Lisinopril. Lisinopril (MK-521) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks.
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Vonedrine-d3 hydrochloride
0 ImagesCat. No.: HY-W701918CAS No.: 1246820-88-1Synonyms: Phenpromethamine-d3 hydrochloride; Methyl-(2-phenyl-propyl)-amine-d3 hydrochlorideVonedrine-d3 (Phenpromethamine-d3 ) hydrochloride is the deuterium labeled Vonedrine hydrochloride.
