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Kinesin Related Products (77)
Related Products (77)
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KIF18A-IN-18
0 ImagesCat. No.: HY-180170CAS No.: 3039911-45-7KIF18A-IN-18 (Compound I) is a KIF18A inhibitor. KIF18A-IN-18 can be used in the research of chromosomally unstable tumors.
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Eg5-IN-3
0 ImagesCat. No.: HY-162518Eg5-IN-3 (5) is an Eg5 inhibitor that targets the novel allosteric pocket (α4/α6/L11). Eg5-IN-3 (5) causes tubulin assembly distortion with irregular morphology, resulting in a typical mitotic arrest similar to Monastrol (HY-101071A).
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KIF14 Human Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS07261KIF14 Human Pre-designed siRNA Set A contains three designed siRNAs for KIF14 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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KIF18A-IN-16
0 ImagesCat. No.: HY-164980CAS No.: 3033981-01-7KIF18A-IN-16 (Compound 15) is a fused ring KIF18A inhibitor. KIF18A-IN-16 can be used in oncology (e.g., colon, breast, lung cancer) studies.
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CK0106023
0 ImagesCat. No.: HY-10084CAS No.: 336115-72-1CK0106023 is a potent and specific allosteric inhibitor of KSP with a Ki value of 12 nM, showing antitumor activity. CK0106023 causes mitotic arrest and growth inhibition in several tumor cell lines. CK0106023 exhibits antitumor activity in tumor-bearing mice.
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KIF18A-IN-17
0 ImagesCat. No.: HY-178511KIF18A-IN-17 (Example 37A) is a KIF18A inhibitor with racemic form with an IC50 of 48 nM. KIF18A-IN-17 exhibits anti-proliferative activity against HT29 cells. KIF18A-IN-17 can be used for the study of cancers such as breast cancer and ovarian cancer.
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4'-Methoxy-S-trityl-L-cysteinol
0 ImagesCat. No.: HY-117440CAS No.: 1338701-15-74'-Methoxy-S-trityl-L-cysteinol is an allosteric inhibitor of vertebrate Kinesin Spindle Protein (KSP). 4'-Methoxy-S-trityl-L-cysteinol significantly enhances its inhibitory activity against NCI60 tumor cells by modifying the trityl and cysteine groups. Its EC50 for bipolar spindle formation is 28 μM, showing stronger inhibitory potency than the parent molecule and monastrol.
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Monastrol (Standard)
0 ImagesCat. No.: HY-101071ARCAS No.: 329689-23-8Synonyms: (±)-Monastrol (Standard)Monastrol (Standard) is the analytical standard of Monastrol (HY-101071A). This product is intended for research and analytical applications. Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5 with an IC50 value of 14 μM.
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BTB-1 (Standard)
0 ImagesCat. No.: HY-101770RCAS No.: 86030-08-2
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Monastroline
0 ImagesCat. No.: HY-124823CAS No.: 462630-41-7Synonyms: HR22C16Monastroline (HR22C16) is an effective and selective inhibitor of the mitotic kinesin Eg5, exhibiting strong cell permeability.
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BRD9876 (Standard)
0 ImagesCat. No.: HY-110208RCAS No.: 32703-82-5BRD9876 (Standard) is the analytical standard of BRD9876 (HY-110208). This product is intended for research and analytical applications. BRD9876 is the "rigor" inhibitor that locks Kinesin-5 (Eg5) in a state with enhanced microtubules (MTs) binding, leading to bundling and stabilization of MTs. BRD9876 interacts with the tyrosine 104 residue that is part of the α4-α6 allosteric binding pocket. BRD9876 specifically targets microtubule-bound Eg5 and selectively inhibits myeloma over CD34 cells. BRD9876 has the potential for multiple myeloma (MM) research.
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NHS-Ala-Ala-Asn-active metabolite
0 ImagesCat. No.: HY-157338CAS No.: 2231135-69-4NHS-Ala-Ala-Asn-active metabolite is a cleavable antibody-drug conjugate (ADC) linker for synthesis of kinesin spindle protein (KSP)inhibitor.
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Ispinesib (Standard)
0 ImagesCat. No.: HY-50759RCAS No.: 336113-53-2Synonyms: SB-715992 (Standard); CK-0238273 (Standard)Ispinesib (Standard) is the analytical standard of Ispinesib. This product is intended for research and analytical applications. Ispinesib is a specific inhibitor of kinesin spindle protein (KSP), with a Ki app of 1.7 nM.
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UA62784
0 ImagesCat. No.: HY-110090CAS No.: 313367-92-9UA62784 is a microtubule polymerization inhibitor that interacts with tubulin dimers. UA62784 is a novel specific inhibitor of centromere protein E (CENP-E) kinesin. UA62784 can be used for the study of pancreatic cancer.
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Paprotrain (Standard)
0 ImagesPaprotrain (Standard) is the analytical standard of Paprotrain (HY-101298). This product is intended for research and analytical applications. Paprotrain is a cell-permeable inhibitor of the kinesin MKLP-2, inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM and shows a moderate inhibition activity on DYRK1A with an IC50 of 5.5 μM.
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KSP-IN-1
0 ImagesCat. No.: HY-179355CAS No.: 609814-45-1KSP-IN-2 (compound 12) is a kinesin spindle protein (KSP) inhibitor with an IC50 of 450 nM.
