Ligands for Target Protein for PROTAC Control

BTK ligand 12 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). BTK ligand 12 can serve as an active control for the target protein ligand of NRX-0492 (HY-153357).

(R)-I-BET762 carboxylic acid, the R-enantiomer of I-BET762 carboxylic acid (HY-107443). I-BET762 carboxylic acid is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid is a BRD4 inhibitor with a pIC₅₀ value of 5.1.

mTOR ligand 1 (compound T2) is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). mTOR ligand 1 can serve as an active control for MHY1485 (HY-B0795, the target protein ligand of PD-M6 (HY-176166).

Temozolomide-amino hydrochloride (compound 8) is an activity control for the target protein ligand of Naph-Se-TMZ (HY-169433).

RSL3-4-Me is the active control of the target protein ligand Demethyl-RSL3 (HY-135832), which can be used for the synthesis of PROTAC .

Palbociclib-CH2COOH is a Ligands for Target Protein for PROTACs. Palbociclib-CH2COOH can serve as an active control for the target protein ligand of CPD-39 (HY-168664) and CPD-10 (HY-168660).

EA-89-Succinic acid (Compound 26) is the active control of the target protein ligand EA-89 (HY-170314), which can be used for the synthesis of PROTAC .

CCS1477a is the active form of the target protein ligand of PROTAC degrader MJP6412 (HY-168201).

(R)-I-BET762 carboxylic acid (Standard) is the analytical standard of (R)-I-BET762 carboxylic acid (HY-107443A). This product is intended for research and analytical applications. (R)-I-BET762 carboxylic acid, the R-enantiomer of I-BET762 carboxylic acid (HY-107443). I-BET762 carboxylic acid is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid is a BRD4 inhibitor with a pIC₅₀ value of 5.1.