EA-89
EA-89 is a potent and selective BRD9 inhibitor with antitumor activity. EA-89 is a Ligand for Target Protein for PROTAC. EA-89 can be used to synthesize PROTAC QA-68 (HY-150797).
For research use only. We do not sell to patients.
- Formula: C31H38N4O4S2
- Molecular Weight:594.79
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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BRD9 |
EA-89 (0-3.2 μM; 1-7 days) inhibits cell proliferation and expression of BRD9, c-MYC and c-MYB in human leukemia cell lines[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:SKM-1 cells
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Concentration:0, 10, 100, 1000 nM
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Incubation Time:24 h
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Result:Reduced the levels of c-MYC and c-MYB.
Chemical Information
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Molecular Weight 594.79
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Formula C31H38N4O4S2
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SMILES
CCCN1C=C(C2=CC=C(N(CC3CCNCC3)C=C4C)C4=C2)C5=C(C=C(S5)C(NC6CCS(CC6)(=O)=O)=O)C1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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