1. Signaling Pathways
  2. Neuronal Signaling
  3. Monoamine Oxidase
  4. MAO-A Isoform
  5. MAO-A Inhibitor

MAO-A Inhibitor

MAO-A Inhibitors (38):

Cat. No. Product Name Effect Purity
  • HY-A0091
    Pargyline hydrochloride
    Inhibitor 99.91%
    Pargyline hydrochloride is an irreversible monoamine oxidase (MAO) inhibitor with Kis of 13 μM and 0.5 μM for MAO-A and MAO-B, respectively.
  • HY-14605
    Rasagiline mesylate
    Inhibitor 99.66%
    Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC50s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively.
  • HY-70057
    Safinamide
    Inhibitor 99.95%
    Safinamide is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 µM) over MAO-A (IC50=580 µM).
  • HY-14605A
    Rasagiline
    Inhibitor 99.88%
    Rasagiline (R-AGN1135) is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC50s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively.
  • HY-A0091A
    Pargyline
    Inhibitor 99.82%
    Pargyline is an irreversible monoamine oxidase (MAO) inhibitor with Kis of 13 μM and 0.5 μM for MAO-A and MAO-B, respectively.
  • HY-17447A
    Tranylcypromine hydrochloride
    Inhibitor
    Tranylcypromine hydrochloride (SKF 385 hydrochloride) is an irreversible inhibitor of lysine-specific demethylase 1 (LSD1/BHC110) and monoamine oxidase (MAO).
  • HY-151596
    MAO-A/5-HT2AR-IN-1
    Inhibitor
    MAO-A/5-HT2AR-IN-1 (compound I14) is a potent MAO-A and 5-HT2AR dual inhibitor, with IC50 values of 0.004 and 0.014 μM, respectively.
  • HY-15386
    Cimoxatone
    Inhibitor
    Cimoxatone (MD 780515) is a reversible, selectively and orally active type A monoamine oxidase (MAO-A) inhibitor.
  • HY-B0534
    Moclobemide
    Inhibitor 99.63%
    Moclobemide (Ro111163) is a brain-penetrant and reversible monoamine oxidase (MAO-A) inhibitor with an IC50 of 6.061 μM for hMAO-A.
  • HY-W008566
    Norharmane
    Inhibitor 98.49%
    Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC50 values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively.
  • HY-131036
    MAO-IN-M30 dihydrochloride
    Inhibitor 99.25%
    MAO-IN-M30 dihydrochloride is an orally active, brain-permeable, and brain selective irreversible MAO-A (IC50=37 nM) and MAO-B (IC50=57 nM) inhibitor.
  • HY-70057A
    Safinamide mesylate
    Inhibitor 99.18%
    Safinamide (FCE 26743; EMD 1195686) mesylate is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 µM) over MAO-A (IC50=580 nM).
  • HY-101392
    Harmane
    Inhibitor 99.81%
    Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations.
  • HY-N2554
    Osthenol
    Inhibitor 98.91%
    Osthenol (Ostenol), a prenylated coumarin isolated from the dried roots of Angelica pubescens, is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM).
  • HY-B1558A
    Bifemelane hydrochloride
    Inhibitor 98.83%
    Bifemelane hydrochloride (MCI-2016) is a potent, selective and competitive inhibitor of monoamine oxidase A (MAO-A), with a Ki of 4.20 μM.
  • HY-142706
    MAO A/HDAC-IN-1
    Inhibitor
    MAO A/HDAC-IN-1 is a dual inhibitor of monoamine oxidase A (MAO A) and HDAC.
  • HY-144758
    LSD1-IN-17
    Inhibitor
    LSD1-IN-17 (compound 5b) is a potent LSD1 inhibitor.
  • HY-119885A
    (±)-Amiflamine
    Inhibitor
    (±)-Amiflamine (FLA 336) is a potent monoamine oxidase-A (MAO-A) inhibitor with a pIC50 of 5.57.
  • HY-152109
    AChE/MAO-IN-1
    Inhibitor
    AChE/MAO-IN-1 (Compound D28) is a potent AChE, MAO-A and MAO-B inhibitor with IC50s of 0.0248, 0.0409 and 0.1108 μM against human AChE, MAO-B and MAO-A, respectively.
  • HY-151208
    MAO-B-IN-16
    Inhibitor
    MAO-B-IN-16 is a selective monoamine oxidase B (MAO-B) inhibitor, with an IC50 of 1.55 µM.