2. Signaling Pathways
  3. NF-κB
  4. NF-κB
  5. NF-κB Control

NF-κB Control

NF-κB Isoform Comparison

NF-κB Controls (7):

Cat. No. Product Name Effect Purity
  • HY-112433A
    (S)-NIK SMI1
    		Control 99.28%
    (S)-NIK SMI1 is the isomer of NIK SMI1 (HY-112433), and can be used as an experimental control. NIK SMI1 is a potent, selective NF-κB inducing kinase (NIK) inhibitor, which inhibits NIK-catalyzed hydrolysis of ATP to ADP with IC50 of 0.23±0.17 nM.
  • HY-106029
    4α-TPA
    		Control 99.0%
    4α-TPA is an inactive form of TPA, and is used as a negative control for TPA-activated events.
  • HY-P2670
    SN50M
    		Control
    SN50M, a mutant peptide of SN50 (HY-P0151), is a cell membrane-permeable inactive control peptide.
  • HY-N17909
    Broussin
    		Control
    Broussin ((S)-7-hydroxy-4'-methoxyflavane) is a flavane compound present in the branches and twigs of Broussonetia papyrifera. Broussin shows no significant antioxidant activity.
  • HY-N9765
    threo-Guaiacylglycerol β-coniferyl ether
    		Control
    threo-Guaiacylglycerol β-coniferyl ether (compound 9) is a potentially active compound, but its inhibitory activity against NF-κB, nitric oxide production, aromatase, quinone reductase 2, and cyclooxygenase (COX-1/-2) is not significant. threo-Guaiacylglycerol β-coniferyl ether can be naturally extracted from the 95% ethanol extract of the whole plant of Lepisorus contortus (Christ) Ching (a plant of the Polypodiaceae family).
  • HY-P10897A
    SjDX5-271v
    		Control
    SjDX5-271v is a negative control of SjDX5-271 (HY-P10897). SjDX5-271 is a small 3 kDa peptide. SjDX5-271 inhibits the TLR4/MyD88/NF-κB signaling pathway. SjDX5-271 induces cell polarization. SjDX5-271 alleviats hepatic inflammation. SjDX5-271 protects mice against liver ischemia-reperfusion injury.
  • HY-124281A
    9(S)-PAHSA
    		Control
    9(S)-PAHSA is a S-enantiomer of 9-PAHSA. 9-PAHSA is an orally available anti-inflammatory lipid that lowers blood sugar and reduces inflammation.