Nucleoside Antimetabolite/Analog
Nucleoside analogues are molecules that act like nucleosides in DNA synthesis. They include a range of antiviral products used to prevent viral replication in infected cells. Nucleoside analogues can be used against hepatitis B virus, hepatitis C virus, herpes simplex, and HIV. Once they are phosphorylated, they work as antimetabolites by being similar enough to nucleotidesto be incorporated into growing DNA strands. Less selective nucleoside analogues are used as chemotherapy agents to treat cancer, eg gemcitabine and 5-FU. Antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of normal metabolism. Such substances are often similar in structure to the metabolite that they interfere with, such as the antifolates that interfere with the use of folic acid. The presence of antimetabolites can have toxic effects on cells, such as halting cell growth and cell division, so these compounds are used as chemotherapy for cancer.
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Nucleoside Antimetabolite/Analog Related Products (2437)
Related Products (2437)
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2′,3′-Dideoxy-3′-fluoroadenosine
0 ImagesCat. No.: HY-154038CAS No.: 87418-35-72′,3′-Dideoxy-3′-fluoroadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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5-Fluoro-3’-beta-C-methyluridine
0 ImagesCat. No.: HY-1541365-Fluoro-3’-beta-C-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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2-Amino-6-chloropurine-9-beta-D-(2’-deoxy-3’,5’-di-O-(p-toluoyl))riboside
0 ImagesCat. No.: HY-W551230CAS No.: 35095-93-32-Amino-6-chloropurine-9-beta-D-(2’-deoxy-3’,5’-di-O-(p-toluoyl))riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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2’-Deoxy-2’-fluoro- N3-(2S)-(2-amino-3-carbonyl)-propyluridine
0 ImagesCat. No.: HY-1547262’-Deoxy-2’-fluoro- N3-(2S)-(2-amino-3-carbonyl)-propyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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3’-beta-C-Methylcytidine
0 ImagesCat. No.: HY-152394CAS No.: 20724-72-5
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3’-O-(2-Methoxyethyl)-2-aminoadenosine
0 ImagesCat. No.: HY-152646CAS No.: 256224-02-93’-O-(2-Methoxyethyl)-2-aminoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
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2′-Deoxy-2-hydrazinyladenosine
0 ImagesCat. No.: HY-154559CAS No.: 1000296-26-32′-Deoxy-2-hydrazinyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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3α,7α-Dihydroxy-5β-cholestan-26-al
0 ImagesCat. No.: HY-180593CAS No.: 1029053-18-63α,7α-Dihydroxy-5β-cholestan-26-al is a nucleoside metabolite.
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TLR7 agonist 10
0 ImagesCat. No.: HY-149071CAS No.: 2389988-34-3TLR7 agonist 10 is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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3'OMe-m7GpppAmpG ammonium solution (100 mM) (GMP Like)
0 ImagesCat. No.: HY-145973AGLSynonyms: m7(3'OMeG)(5')ppp(5')(2'OMeA)pG ammonium solution (100 mM) (GMP Like)3'OMe-m7GpppAmpG ammonium solution (100 mM) (GMP Like) (m7(3'OMeG)(5')ppp(5')(2'OMeA)pG ammonium solution (100 mM) (GMP Like)) is a GMP-like grade of 3’OMe-m7GpppAmpG. 3’OMe-m7GpppAmpG (m7(3'OMeG)(5')ppp(5')(2'OMeA)pG) ammonium solution (100 mM) is a trinucleotide Cap1 analog with the structure m7 (3'OMeG)(5') ppp (5')(2'OMeA) pG, and also functions as a cis-acting ligase ribozyme inhibitor. 3’OMe-m7GpppAmpG ammonium solution (100 mM) effectively reduces free 5'-triphosphate groups on RNA transcripts, thereby enabling efficient co-transcriptional capping of in vitro transcribed mRNA. 3’OMe-m7GpppAmpG ammonium solution (100 mM) is not only widely used in the preparation of modified mRNA including trivalent influenza vaccine candidates, but also applicable to studies related to SARS-CoV-2 infection and other relevant research.
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3’-Deoxy-O6-methyl inosine
0 ImagesCat. No.: HY-154201CAS No.: 945215-53-23’-Deoxy-O6-methyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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3’-Deoxy-3’-fluoro-2-thiouridine
0 ImagesCat. No.: HY-152754CAS No.: 439579-24-53’-Deoxy-3’-fluoro-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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6-Chloro-2-iodopurine-9-riboside
0 ImagesCat. No.: HY-21978CAS No.: 313477-85-99H-Purine, 6-chloro-2-iodo-9-β-D-ribofuranosyl- (6-CHLORO-2-IODOPURINE-9-RIBOSIDE) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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3’-Azido-3’-deoxy-4-deoxyuridine
0 ImagesCat. No.: HY-152985CAS No.: 2095417-07-36-Chloro-N1-(trimethylsilylethoxymethyl)pseudouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents. 3’-Azido-3’-deoxy-4-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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ADP-β-D-ribofuranose-13C15
0 ImagesCat. No.: HY-157906SADP-β-D-ribofuranose-13C15 is the 13C-labeled ADP-β-D-ribofuranose (HY-157906). ADP-β-D-ribofuranose is a nucleotide derivative composed of ADP and a ribose unit. ADP-β-D-ribofuranose can be produced by NAD+ catalysis.
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2-Amino-3’-deoxy-3’-fluoroadenosine
0 ImagesCat. No.: HY-152487CAS No.: 125391-75-52-Amino-3’-deoxy-3’-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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α-Phocaecholic acid
0 ImagesCat. No.: HY-W1130518CAS No.: 6879-45-4α-Phocaecholic acid is a nucleoside metabolite.
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2'-O-Methyl-5-iodouridine
0 ImagesSynonyms: 5-Iodo-2'-O-methyluridine2’-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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3′-Azido-2′,3′-dideoxy-5-hydroxyuridine
0 ImagesCat. No.: HY-149070CAS No.: 111495-90-03′-Azido-2′,3′-dideoxy-5-hydroxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
![6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine](https://file.medchemexpress.com/product_pic/hy-154047.gif "Click to View 6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine Product Detail")
0 ImagesCat. No.: HY-1540476-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects.
