2. Signaling Pathways
  3. PI3K/Akt/mTOR
  4. PTEN
  5. PTEN Inducer

PTEN Inducer

PTEN Inducers (2):

Cat. No. Product Name Effect Purity
  • HY-160093
    SQLE-IN-1
    		Inducer 99.21%
    SQLE-IN-1 (compound 19) is a squalene epoxidase (SQLE) inhibitor. SQLE-IN-1 inhibits the proliferation and migration of Huh7 cells. SQLE-IN-1 inhibits the cell cholesterol generation. SQLE-IN-1 increases the expression of PTEN and inhibits PI3K and AKT.
  • HY-N7325
    Valerosidate
    		Inducer
    Valerosidate is an OX2R antagonist. Valerosidate increases expression of tumor suppressor proteins p53 and PTEN, selectively reduces colon cancer cell viability, and suppresses colon cancer cell migration. Valerosidate can be used for the research of colon cancer and insomnia.