2. Signaling Pathways
  3. GPCR/G Protein
  4. Arrestin
  5. Arrestin Inducer

Arrestin Inducer

Arrestin Isoform Comparison

Arrestin Inducers (2):

Cat. No. Product Name Effect Purity
  • HY-174466
    5-HT2AR ligand 1
    		Inducer
    5-HT2AR ligand 1 (Compound 2 cis) is a 5-HT2AR ligand with nanomolar affinity for 5-HT2AR (Ki: 32 nM). 5-HT2AR ligand 1 is capable of inducing β-arrestin 2 recruitment. 5-HT2AR ligand 1 can be used in the research of neurological diseases.
  • HY-115643
    AZ13581837
    		Inducer
    AZ13581837 is an orally active GPR120 agonist with an EC50 of 5.2 nM for human GPR120. AZ13581837 signals through Gαq, Gαs, and β-arrestin pathways, reduces cAMP production, stimulates GLP-1 secretion, induces glucose lowering, and increases insulin secretion. AZ13581837 can be used for the research of type 2 diabetes.