Drug Derivative
Drug derivative
Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.
References:
- [1]. Vardanyan RS, et al. Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications. Future Med Chem. 2014 Mar;6(4):385-412.x
- [2]. Ghosh AK, et al. Urea Derivatives in Modern Drug Discovery and Medicinal Chemistry. J Med Chem. 2020 Mar 26;63(6):2751-2788.x
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Drug Derivative Related Products (4062)
Related Products (4062)
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Aesculioside B
0 ImagesCat. No.: HY-N16846CAS No.: 106310-33-2Aesculioside B is a natural triterpene.
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JQ-1 (carboxylic acid)-NHS
0 ImagesCat. No.: HY-181847CAS No.: 2785405-22-1
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ent-9-Hydroxy-15-oxokaur-16-en-19-oic acid β-D-glucopyranosyl ester
0 ImagesCat. No.: HY-N9157CAS No.: 81263-96-9ent-9-Hydroxy-15-oxokaur-16-en-19-oic acid β-D-glucopyranosyl ester is a natural diterpene.
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NRMA-7
0 ImagesCat. No.: HY-164507CAS No.: 2375659-14-4NRMA-7 is a BBB-penetrable small molecule nuclear receptor modulator. NRMA-7 can be used in the study of central nervous system diseases.
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BMY 25282
0 ImagesCat. No.: HY-105361CAS No.: 88949-01-3Synonyms: BL 6782BMY 25282 (BL 6782) is a mitomycin C (MMC) analog. BMY 25282 catalyzes oxygen activation in hepatocytes. BMY 25282 overcomes MMC tolerance in colon cancer cells and mouse models of colon cancer. BMY 25282 inhibits tumor growth in mouse models of leukemia and melanoma. BMY 25282 can be used in research on cancers such as leukemia, melanoma, and colon cancer.
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Breynioside A
0 ImagesCat. No.: HY-N16851CAS No.: 63555-02-2Breynioside A is a natural phenolic compound.
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WAY-620473
0 ImagesWAY-620473 is an active molecule.
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9β-Hydroxynootkatone
0 ImagesCat. No.: HY-N17179CAS No.: 226547-01-99β-Hydroxynootkatone is a natural sesquiterpene.
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LY 221501
0 ImagesCat. No.: HY-116081CAS No.: 145512-35-2LY 221501 is an active compound.
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Periplocoside O
0 ImagesCat. No.: HY-137060CAS No.: 116709-67-2Periplocoside O is a natural steroid.
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Rodorubicin
0 ImagesCat. No.: HY-105035CAS No.: 96497-67-5Synonyms: Cytorhodin S; HLB 817Rodorubicin (Cytorhodin S) is a tetraglycosidic anthracycline with preclinical antitumor activity.
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Mitoquidone
0 ImagesCat. No.: HY-128470CAS No.: 91753-07-0Synonyms: GR-30921Mitoquidone (GR-30921) is is the first member of a group of pentacyclic pyrroloquinones. Mitoquidone shows good activity in a range of experimental solid tumour models. Mitoquidone can be used for the research of anti-cancer.
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Cyphostemmin B
0 ImagesCat. No.: HY-N7978CAS No.: 220328-16-5Cyphostemmin B is a natural product that can be found in Parthenocissusquinquefolia(L.) Planch..
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Glutathione sulfinanilide
0 ImagesCat. No.: HY-182251CAS No.: 70475-39-7Synonyms: GSOANGlutathione sulfinanilide (GSOAN) is a derivative of Nitrosobenzene (HY-121641). Glutathione sulfinanilide can be generated by the reaction of Nitrosobenzene with GSH. Glutathione sulfinanilide is degradable in rat liver homogenate.
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C6-Amide-(PEG)n-CH3
0 ImagesCat. No.: HY-148153C6-Amide-(PEG)n-CH3 (n=310) is an active compound. C6-Amide-(PEG)n-CH3 is a small molecule moiety for PEGylation in Egaptivon pegol (HY-147079) that can be used for the research of platelet dysfunction disorders.
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MRZ-8676
0 ImagesCat. No.: HY-133059CAS No.: 872122-36-6MRZ-8676 is an active compound.
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3,4-Dihydroxybenzoyllupeol
0 ImagesCat. No.: HY-N9059CAS No.: 2231323-99-03,4-Dihydroxybenzoyllupeol is a natural triterpene.
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A70450
0 ImagesCat. No.: HY-117077CAS No.: 142928-23-2A70450 is an active compound.
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16-HydroxyCapsaicin
0 ImagesCat. No.: HY-N17547CAS No.: 112848-19-816-HydroxyCapsaicin is a natural product that can be found in chili.
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Gibberellic acid (Standard)
0 ImagesGibberellic acid (Standard) is the analytical standard of Gibberellic acid (GA3) (HY-N1964). This product is intended for research and analytical applications. Gibberellic acidis a natural plant growth regulator with oral bioactivity. Gibberellic acid governs multiple plant developmental events, including seed germination, cell elongation, floral organ formation, and rice spikelet fertility. Gibberellic acid optimizes root morphology and secondary metabolite production in Echinacea purpurea hairy roots, and serves as a bioactive seed priming agent to improve chilling stress tolerance in chickpea. Gibberellic acid mediates modulation of enzyme activity and secondary metabolism in plants and exerts tissue-specific regulatory effects on antioxidant systems and lipid peroxidation in rats. Gibberellic acid can be used in studies of plant growth, metabolism, and abiotic stress responses.
