2. Signaling Pathways
  3. Immunology/Inflammation
  4. FAP
  5. FAP Antagonist

FAP Antagonist

FAP Antagonist (1):

Cat. No. Product Name Effect Purity
  • HY-182434
    CL 118326
    		Antagonist
    CL 118326 is a potent, selective, competitive inhibitor of mammalian pancreatic phospholipase A2 (PLA2) and a weak antagonist of platelet-activating factor receptor (PAF receptor). CL 118326 competitively inhibits mammalian pancreatic PLA2 (porcine: IC50 = 1.55 μg/mL), and shows no activity against snake venom or bee venom PLA2. CL 118326 inhibits PAF-induced and thrombin-induced platelet aggregation, as well as the release of leukotriene (LTC4) and histamine from basophil-enriched leukocytes. CL 118326 can be used for research on inflammation and allergic reactions.