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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10876):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-50767S1
    Palbociclib-d4 hydrochloride
    Palbociclib-d4 (hydrochloride) is the deuterium labeled Palbociclib hydrochloride. Palbociclib (PD 0332991) is a selective CDK4 and CDK6 inhibitor with IC50s of 11 and 16 nM, respectively. Palbociclib has the potential for ER-positive and HER2-negative breast cancer research.
    Palbociclib-d<sub>4</sub> hydrochloride
  • HY-150987S
    2,2',6-Trichloro bisphenol A-d11
    2,2',6-Trichloro bisphenol A-d11 is the deuterium labeled 2,2',6-Trichloro bisphenol A.
    2,2',6-Trichloro bisphenol A-d<sub>11</sub>
  • HY-W010593S
    Ethylenethiourea-d4
    Ethylenethiourea-d4 is the deuterium labeled Ethylenethiourea. Ethylenethiourea is a degradation product of the ethylenebisthiocarbamate group of fungicides. Ethylenethiourea is tumorigenic and teratogenic. Ethylenethiourea is orally active.
    Ethylenethiourea-d<sub>4</sub>
  • HY-W746295
    3-Hydroxypyridine-d5
    3-Hydroxypyridine-d5 is the deuterium labeled 3-Hydroxypyridine (HY-Y1129). 3-Hydroxypyridine is a compound that can be isolated from bamboo grass. As an endogenous photosensitizer present in human skin, 3-hydroxypyridine can mediate oxidative stress, proliferation inhibition and apoptosis of skin cells through UVA/UVB excitation.
    3-Hydroxypyridine-d<sub>5</sub>
  • HY-W745874
    3-(4-Chlorophenyl)-1-isoindolinone-d4
    3-(4-Chlorophenyl)-1-isoindolinone-d4 is the deuterium labeled 3-(4-Chlorophenyl)isoindolin-1-one (HY-W600173).
    3-(4-Chlorophenyl)-1-isoindolinone-d<sub>4</sub>
  • HY-146834S
    1,3-18:0 DG-d5
    1,3-18:0 DG-d5 is deuterium labeled 1,3-18:0 DG.
    1,3-18:0 DG-d<sub>5</sub>
  • HY-W778114
    Guanine-13C2,7-15N
    Guanine-13C2,15N is the 13C- and 15N-labeled Guanine (HY-Y1055). Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects.
    Guanine-<sup>13</sup>C<sub>2</sub>,7-<sup>15</sup>N
  • HY-W751066
    2-Linoleoyl-rac-glycerol-O-TIPS-d5
    2-Linoleoyl-rac-glycerol-O-TIPS-d5 is the deuterium labeled 2-Linoleoyl-rac-glycerol-O-TIPS.
    2-Linoleoyl-rac-glycerol-O-TIPS-d<sub>5</sub>
  • HY-W013160S
    Dioctyl Terepthalate-d4
    Dioctyl Terepthalate-d4 is the deuterium labeled Dioctyl Terepthalate.
    Dioctyl Terepthalate-d<sub>4</sub>
  • HY-N0136S
    Taxifolin-d3
    Taxifolin-d3 is deuterium labeled Taxifolin. Taxifolin ((+)-Dihydroquercetin) exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity.
    Taxifolin-d<sub>3</sub>
  • HY-W067056S1
    Methyl(E)-cinnamate-d7
    99.1%
    Methyl(E)-cinnamate-d7 is the deuterium labeled Methyl (E)-cinnamate. Methyl (E)-cinnamate (Methyl (E)-3-phenylpropenoate) is a natural flavor compound with anti-inflammatory properties found in Alpinia katsumadai Hayata. Methyl (E)-cinnamate induces apoptosis via reduced anti-apoptotic protein expression, increased TUNEL-positive cells, and apoptotic morphological changes. Methyl (E)-cinnamate can be used for the research of abnormalities of osteoblast function in bone diseases.
    Methyl(E)-cinnamate-d<sub>7</sub>
  • HY-B1256S
    Cefuroxime-d3
    Cefuroxime-d3 is deuterium labeled Cefuroxime (sodium). Cefuroxime sodium is an orally active second-generation cephalosporin antibiotic with increased stability to β-lactamase. Cefuroxime sodium has a broad spectrum activity against Gram-positive and Gram-negative bacteria.
    Cefuroxime-d<sub>3</sub>
  • HY-W752004
    (2R)-Mitiglinide-d10 calcium
    (2R)-Mitiglinide-d10 calcium (KAD-1229-d10 Calcium ) is the deuterium labeled (2R)-Mitiglinide calcium.
    (2R)-Mitiglinide-d<sub>10</sub> calcium
  • HY-W743830
    Methyl Lithocholate-d7
    Methyl Lithocholate-d7 is the deuterium labeled Methyl Lithocholate.
    Methyl Lithocholate-d<sub>7</sub>
  • HY-W744298
    Trandolapril-d3
    Trandolapril-d3 is the deuterium labeled Trandolapril (HY-B0592). Trandolapril (RU44570) is a nonsulfhydryl proagent that is hydrolysed to the active diacid Trandolaprilat. Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that has been used in the treatment of hypertension and congestive heart failure (CHF), and after myocardial infarction (MI).
    Trandolapril-d<sub>3</sub>
  • HY-118189S
    Misoprostol acid-d5
    Misoprostol acid-d5 is deuterium labeled Misoprostol acid. Misoprostol acid is an active metabolite of Misoprostol. Misoprostol is a synthetic analogue of prostaglandin E1 (PGE1), extensively absorbed, and undergoes rapid de-esterification to Misoprostol acid in the gastrointestinal tract after oral administration. Misoprostol can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers. Misoprostol is an oral agent used to induce labor.
    Misoprostol acid-d<sub>5</sub>
  • HY-W752883
    Fmoc-D-Ala-OH-d4
    Fmoc-D-Ala-OH-d4 is the deuterium labeled Fmoc-D-Ala-OH (HY-W008072). Fmoc-D-Ala-OH is an alanine derivative.
    Fmoc-D-Ala-OH-d<sub>4</sub>
  • HY-B0368S
    Captopril-d3
    Captopril-d3 is deuterium labeled Captopril. Captopril (SQ 14225), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM) and has been widely used for research of hypertension and congestive heart failure. Captopril is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 7.9 μM.
    Captopril-d<sub>3</sub>
  • HY-N0521AS
    (+)-Gallocatechin-13C3
    (+)-Gallocatechin-13C3 is the 13C-labeled (+)-Gallocatechin. (+)-Gallocatechin is a polyphenol compound from green tea, possesses anticancer activity.
    (+)-Gallocatechin-<sup>13</sup>C<sub>3</sub>
  • HY-W752476
    Succinyladenosine-13C4
    Succinyladenosine-13C4 (N6-Succinyl adenosine-13C4) is the 13C-labeled Succinyladenosine (HY-113284). Succinyladenosine, the metabolic product of dephosphorylation of intracellular adenylosuccinic acid (S-AMP) by cytosolic 5-nucleotidase, is a biochemical marker of adenylosuccinase (ASL) deficiency.
    Succinyladenosine-<sup>13</sup>C<sub>4</sub>