2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10876):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0380S2
    Trimebutine-d3 hydrochloride
    Trimebutine-d3 hydrochloride is deuterium labeled Trimebutine hydrochloride. Trimebutine hydrochloride is a multi-target inhibitor and opioid receptor agonist with antimuscarinic activity. Trimebutine hydrochloride inhibits L-type Ca2+ channels and large-conductance calcium-activated potassium channels (BKCa channels), thereby inhibiting extracellular calcium influx and potassium ion efflux. Trimebutine hydrochloride also targets Toll-like receptors, inhibits Toll-like receptor 2/4/7/8/9 signals, and inhibits LPS-induced IRAK1 activation, as well as ERK1/2, JNK and NF-κB activation, thereby exerting anti-inflammatory effects. Trimebutine hydrochloride also induces tumor cell apoptosis by inhibiting the AKT/ERK pathway. Trimebutine hydrochloride also inhibits excessive contraction of smooth muscle and can be used in the study of gastrointestinal disorders such as irritable bowel syndrome (IBS).
    Trimebutine-d<sub>3</sub> hydrochloride
  • HY-W723905
    Morpholine-4-carbonyl-d8 chloride
    Morpholine-4-carbonyl-d8 chloride is the deuterium labeled Morpholine-4-carbonyl chloride.
    Morpholine-4-carbonyl-d<sub>8</sub> chloride
  • HY-W131351S
    N-heptadecane-d36
    N-heptadecane-d36 is the deuterium labeled N-heptadecane.
    N-heptadecane-d<sub>36</sub>
  • HY-W005355S12
    Sodium 2-oxobutanoate-d5
    Sodium 2-oxobutanoate-d5 is the deuterium labeled Sodium 2-oxobutanoate (HY-W005355). Sodium 2-oxobutanoate is an organic compound commonly used as a food additive and industrial raw material. It can be used as an acidity regulator, leavening agent and preservative, and is often used in the fields of bread, baked goods and canning. In addition, the compound is used in the production of certain industrial products, such as in plastics, textiles and dyes.
    Sodium 2-oxobutanoate-d<sub>5</sub>
  • HY-143817S
    Clopidogrel-d3 (hydrochloride)
    Clopidogrel-d3 (hydrochloride) is the deuterium labeled Clopidogrel hydrochloride.
    Clopidogrel-d<sub>3</sub> (hydrochloride)
  • HY-144143S
    N-Desmethyl Olopatadine-d3 (hydrochloride)
    N-Desmethyl Olopatadine-d3 (hydrochloride) is the deuterium labeled N-Desmethyl Olopatadine hydrochloride.
    N-Desmethyl Olopatadine-d<sub>3</sub> (hydrochloride)
  • HY-N0215S6
    DL-Phenylalanine-d5 hydrochloride
    DL-Phenylalanine-d5 (hydrochloride) is the deuterium labeled DL-Phenylalanine hydrochloride. L-Phenylalanine hydrochloride is an essential amino acid isolated from Escherichia coli. L-Phenylalanine hydrochloride is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine hydrochloride is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine hydrochloride is widely used in the production of food flavors and pharmaceuticals.
    DL-Phenylalanine-d<sub>5</sub> hydrochloride
  • HY-B0369AS
    Orphenadrine-d3 citrate
    Orphenadrine-d3 (citrate) is the deuterium labeled Orphenadrine citrate. Orphenadrine citrate is a NMDA receptor antagonist with Ki of 6.0 +/- 0.7 μM, HERG potassium channel blocker.
    Orphenadrine-d<sub>3</sub> citrate
  • HY-146866S
    1-Heptadecanoyl-2-docosatetraenoyl-sn-glycero-3-phospho- L-serine-d5 sodium
    1-Heptadecanoyl-2-docosatetraenoyl-sn-glycero-3-phospho- L-serine-d5 (sodium) is deuterium labeled 1-Heptadecanoyl-2-docosatetraenoyl-sn-glycero-3-phospho- L-serine (sodium).
    1-Heptadecanoyl-2-docosatetraenoyl-sn-glycero-3-phospho- L-serine-d<sub>5</sub> sodium
  • HY-15494S1
    Picropodophyllin-d6
    Picropodophyllin-d6 (AXL1717-d6) is deuterium labeled Picropodophyllin. Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 1 nM.
    Picropodophyllin-d<sub>6</sub>
  • HY-W707400
    Ethane-1,2-diyl-d4 dibenzoate
    Ethane-1,2-diyl-d4 dibenzoate is the deuterium labeled Ethylene Glycol Dibenzoate (HY-W103900).
    Ethane-1,2-diyl-d<sub>4</sub> dibenzoate
  • HY-W726231
    4-Methylsyringol-d6
    4-Methylsyringol-d6 is the deuterium labeled 4-Methylsyringol (HY-W100715). 4-Methylsyringol is a natural product that can be isolated from hardwood.
    4-Methylsyringol-d<sub>6</sub>
  • HY-B0011AS
    Docetaxel-d5 trihydrate
    Docetaxel-d5 (trihydrate) is the deuterium labeled Docetaxel (Trihydrate). Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule?depolymerization with an IC50 value of 0.2 μM. Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of?bcl-2?and?bcl-xL?gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis.
    Docetaxel-d<sub>5</sub> trihydrate
  • HY-146716S
    N-Acetyl-S-(N-methyl-carbamoyl)-L-cysteine-d3 dicyclohexylamine
    N-Acetyl-S-(N-methyl-carbamoyl)-L-cysteine-d3 (dicyclohexylamine) is the deuterium labeled N-Acetyl-S-(N-methyl-carbamoyl)-L-cysteine.
    N-Acetyl-S-(N-methyl-carbamoyl)-L-cysteine-d<sub>3</sub> dicyclohexylamine
  • HY-154771S
    Clopidogrelat-13C,d4
    Clopidogrelat-13C,d4 is 13C and deuterated labeled Clopidogrelat.
    Clopidogrelat-<sup>13</sup>C,d<sub>4</sub>
  • HY-10873S2
    N-Desethyl Sunitinib-d5 hydrochloride
    N-Desethyl Sunitinib-d5 (hydrochloride) is a deuterated labeled N-Desethyl Sunitinib. N-Desethyl Sunitinib (SU-12662) is a metabolite of sunitinib. Sunitinib is a potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor with Ki values of 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT, respectively.
    N-Desethyl Sunitinib-d<sub>5</sub> hydrochloride
  • HY-W156412S
    (2S)-2-(Acetylamino)-N,4-dimethylpentanamide-d16
    (2S)-2-(Acetylamino)-N,4-dimethylpentanamide-d16 is the deuterium labeled (2S)-2-(Acetylamino)-N,4-dimethylpentanamide.
    (2S)-2-(Acetylamino)-N,4-dimethylpentanamide-d<sub>16</sub>
  • HY-N0083S2
    Betulin-d3-1
    Betulin-d3-1 is the deuterium labeled Betulin (HY-N0083). Betulin (Trochol), is a sterol regulatory element-binding protein (SREBP) inhibitor with an IC50 of 14.5 μM in K562 cell line.
    Betulin-d<sub>3</sub>-1
  • HY-121427S
    Fluazifop-d3
    Fluazifop-d3 is the deuterium labeled Fluazifop (HY-121427). Fluazifop is a grass-selective herbicide via inhibiting acetyl-CoA carboxylase.
    Fluazifop-d<sub>3</sub>
  • HY-146865S
    1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d5 sodium
    1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d5 (sodium) is deuterium labeled 1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (sodium).
    1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d<sub>5</sub> sodium