2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. LDLR
  5. LDLR Degrader

LDLR Degrader

LDLR Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-P11071
    PCSK9 Inhibitor, EGF-A
    		Degrader
    PCSK9 Inhibitor, EGF-A is a PCSK9 inhibitor with LDLR degradation inhibitory activity and LDLR recycling promoting activity. PCSK9 Inhibitor, EGF-A is a synthetic peptide consisting of 42 amino acid residues, which contains the calcium-binding site of the epidermal growth factor A domain (EGF-A). PCSK9 Inhibitor, EGF-A reduces plasma LDL cholesterol levels by maintaining hepatic LDLR levels and enhancing the clearance capacity of circulating LDL. PCSK9 Inhibitor, EGF-A can be used in research related to hypercholesterolemia, premature atherosclerosis, coronary heart disease and familial hypercholesterolemia.